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Protein Alignment Cht6 and OVGP1

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_002548.3	Gene:	OVGP1 / 5016	HGNCID:	8524	Length:	678	Species:	Homo sapiens

Alignment Length:	731	Identity:	213/731 - (29%)
Similarity:	327/731 - (44%)	Gaps:	113/731 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 WQTLFLLCALAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYLCTHLVYAFGGFTKDNQ 74
            |:.|..:..:....:...:..::|||:|||:..|||.|...|.:::|:|||||::||... .:||
Human     2 WKLLLWVGLVLVLKHHDGAAHKLVCYFTNWAHSRPGPASILPHDLDPFLCTHLIFAFASM-NNNQ 65

  Fly    75 MKPFDKYQDIEQGGYAKFTGLKTYNKQLKTMIAIGGWNEASSRFSPLVASNERRQQFIKNILKFL 139
            :...| .|| |:..|.:|..||..|::|||:::|||||..:|||:.::::...|::||.:::..|
Human    66 IVAKD-LQD-EKILYPEFNKLKERNRELKTLLSIGGWNFGTSRFTTMLSTFANREKFIASVISLL 128

  Fly   140 RQNHFDGIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREAEKTGRTRLLLTMAVPAGIEYI 204
            |.:.|||:||.:.||..| |....||..:...::||...|.:||..|.|.||||:.||......:
Human   129 RTHDFDGLDLFFLYPGLR-GSPMHDRWTFLFLIEELLFAFRKEALLTMRPRLLLSAAVSGVPHIV 192

  Fly   205 DKGYDVPKLNKYLDWFNVLTYDFHSSHEPSVNHHAPLYSLEEDSEYNYDAELNIDYSIKYYLKAG 269
            ...|||..|.:.||:.|||:||.|.|.|....|::||:||.||.:       :..|::.|:.|.|
Human   193 QTSYDVRFLGRLLDFINVLSYDLHGSWERFTGHNSPLFSLPEDPK-------SSAYAMNYWRKLG 250

  Fly   270 ADRDKLVLGIPTYGRSYTLINEESTELGAPAEGPGEQGDATREKGYLAYYEICQTL-KDDPEWTV 333
            |..:||::|||||||::.|:......|.|.|.||...|..|:::|:|||:|||..: .....|..
Human   251 APSEKLIMGIPTYGRTFRLLKASKNGLQARAIGPASPGKYTKQEGFLAYFEICSFVWGAKKHWID 315

  Fly   334 VQPNANVMGPYAYRRNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRGT-CNGKPYPLI 397
            .|     ..|||.:..:|||||:......||.::..:..||.|.|.:|.||.||| |...|:||:
Human   316 YQ-----YVPYANKGKEWVGYDNAISFSYKAWFIRREHFGGAMVWTLDMDDVRGTFCGTGPFPLV 375

  Fly   398 EAAKEAMVEALGLGINEVAKPSGPQKPSRSRSRDNASNRNRLNGKTEAPLSSRRPSATRRPAVSS 462
            ....:.:|.|      |.:..|.||....|....::::..||              |......:.
Human   376 YVLNDILVRA------EFSSTSLPQFWLSSAVNSSSTDPERL--------------AVTTAWTTD 420

  Fly   463 TQAPPPSTTFKLTEAEG--SSLYIGGRASTTPPPPTTPDPGSDFKCEEEGFFQHPRDCKKYYWCL 525
            ::..||.....:||..|  .::.|..|.:|..|...|...|                  |:...|
Human   421 SKILPPGGEAGVTEIHGKCENMTITPRGTTVTPTKETVSLG------------------KHTVAL 467

  Fly   526 D-----SGPSGLGIVAHMFTCPSGLYFNPAADSCDFARNVPCKTKKST------------TAAPV 573
            .     :|...:..|.|....|......|...     ::|....|..|            |..||
Human   468 GEKTEITGAMTMTSVGHQSMTPGEKALTPVGH-----QSVTTGQKTLTSVGYQSVTPGEKTLTPV 527

  Fly   574 -----------------TSTTPA---TTTVRSNRVTAAPTSRPVYPRTTTTTSTTTTTTTTPSTV 618
                             |:.||.   |.|:|.|  |.||..:.|.....|..|...:.|....|:
Human   528 GHQSVTPVSHQSVSPGGTTMTPVHFQTETLRQN--TVAPRRKAVAREKVTVPSRNISVTPEGQTM 590

  Fly   619 ---DEDLEYEEDTDELSPSKSTDAEEDPQVIKELIDLIRKVGGVEQL-EKHLLRNKDGSITLKEN 679
               .|:|..|..|.....:.....|.:.:::.....:|       || |:..|...:..:.:..|
Human   591 PLRGENLTSEVGTHPRMGNLGLQMEAENRMMLSSSPVI-------QLPEQTPLAFDNRFVPIYGN 648

  Fly   680 SATGAATTPSTISKSL 695
            .::..:.||.|...||
Human   649 HSSVNSVTPQTSPLSL 664

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.