DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht6 and Cht2

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	477	Identity:	171/477 - (35%)
Similarity:	252/477 - (52%)	Gaps:	79/477 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFLLCALAYCINE--ASSEGR--------VVCYYTNWSVYRPGTAKFNPQNINPYLCTHLVYAFG 67
            |:||..||...:.  ||...|        ||||.:.|:||||....:..:|.:|.||||:||||.
  Fly    14 LWLLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNLCTHVVYAFA 78

  Fly    68 GF-TKDNQMKPFDKYQDIEQ----GGYAKFTGLKTYNKQLKTMIAIGGWNEASSRFSPLVASNER 127
            |. .....:|..|.:||:::    |||.|.||||..:..||..:|||||||.|:.:|.|||:|..
  Fly    79 GLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNEGSANYSTLVANNLL 143

  Fly   128 RQQFIKNILKFLRQNHFDGIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREAEKTGRTRLL 192
            |.:|:|.:..|:|:.:|||:|||||||..|: ||..||:|:....:|||.||:...       ||
  Fly   144 RGRFVKQVSSFIRKYNFDGLDLDWEYPTQRK-GKPADRENFVLLTKELREEFDEHG-------LL 200

  Fly   193 LTMAVPAGIEYIDKGYDVPKLNKYLDWFNVLTYDFHSSHEPSVNHHAPLYSLEEDSEYNYDAELN 257
            ||.|:.|..:.||:.|||.::::|||:.:::.||:|.|.:..|.::|||.:..:|       .|:
  Fly   201 LTSAIGASKKVIDEAYDVRQISRYLDYLHIMCYDYHGSWDRRVGYNAPLTAPADD-------PLS 258

  Fly   258 IDYSIKYYLKAGADRDKLVLGIPTYGRSYTLINEESTELGAPAEGPGEQGDATREKGYLAYYEIC 322
            :.:||.|.||.||..:|||:|:|.|||::..:  .|..|...:||.|.:|..|||.|:|.|.|||
  Fly   259 VKFSIDYLLKLGAPPEKLVMGLPFYGRTFKTL--ASGFLNDVSEGVGFKGPYTREDGFLGYNEIC 321

  Fly   323 QTLKD---------DPEWTVVQPNANVMGPYAYRRNQW------VGYDDEAIVRKKAEYVVAQGL 372
            |||.:         ||:.:.|...:        .||.:      |.||....:..|..:.:::.|
  Fly   322 QTLSNQTSGWTREWDPQTSQVLAKS--------ERNVFTQEINVVTYDSSRSIANKVLFAMSKRL 378

  Fly   373 GGIMFWAIDNDDFRGTC-------------------NGKPYPLIEAAKEAMVEALGLGINEVAKP 418
            .|:|.|::|.|||.|.|                   :.:.|||:....||.:    |.::|:|.|
  Fly   379 AGVMVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPKRSSQNYPLLRTINEATM----LAVDELAVP 439

  Fly   419 SGPQKPSRSRSRDNASNRNRLN 440
            . ||.........:.|..:|.|
  Fly   440 E-PQPDDSENEIPHGSIADRKN 460

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	145/379 (38%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	153/410 (37%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	144/371 (39%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	152/409 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	188	1.000	Domainoid score	I962
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D48394at33392
OrthoFinder	1	1.000	-	-		FOG0000107
OrthoInspector	1	1.000	-	-		mtm1002
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	7	6.920