DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht6 and Idgf5

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_611321.3	Gene:	Idgf5 / 37104	FlyBaseID:	FBgn0064237	Length:	444	Species:	Drosophila melanogaster

Alignment Length:	444	Identity:	126/444 - (28%)
Similarity:	213/444 - (47%)	Gaps:	72/444 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LLCA-LAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYL--CTHLVYAFGGF-TKDNQM 75
            |||: ||:..:..:..|::||:|...|..|.|.|:.:...:.|.|  |..|||.:.|. ....::
  Fly    13 LLCSFLAFFQSTYAEVGKLVCFYDAQSFVREGPAQMSLAELEPALQFCNFLVYGYAGIDAVTYKI 77

  Fly    76 KPFDKYQDIEQGGYAKFTGLKTYNKQLKTMIAIGGWNEASS-------RFSPLVASNERRQQFIK 133
            |..|.....::..|...|.|:.....::.::::||..:.:|       ::..|:..:|.|:.|..
  Fly    78 KSLDPSLTNDRQHYRHITALRKKYPHVRFLLSVGGDRDVNSEGVADSDKYLRLLEQSEHRKSFQA 142

  Fly   134 NILKFLRQNHFDGIDLDWEYPAHR----EG-------------------GKSRD-RDNYAQFVQE 174
            ::|..|..|.||||||.|::|.:|    :|                   .||.: |:.:|..::|
  Fly   143 SVLAELNNNGFDGIDLAWQFPKNRPKLQQGVFKRVWGSLRGWFSSSSVDEKSEEHREQFATLLEE 207

  Fly   175 LRAEFEREAEKTGRTRLLLTMAVPAGIEYIDKGYDVPKLNKYLDWFNVLTYDFHS-SHEPSV-NH 237
            |:::..|..:       |||:::...:. .:...||||:...:|:.|:.||||.: ..:|.| :.
  Fly   208 LQSDLRRGGQ-------LLTVSMLPHVS-AELFIDVPKVLSNVDFVNLGTYDFQTPERDPKVADL 264

  Fly   238 HAPLYSLEEDSEYNYDAELNIDYSIKYYLKAGADRD--KLVLGIPTYGRSYTLINEESTELGAP- 299
            ..|||::     |:.|...|:.|.::|::...::..  ||.:|:.:|||::.: ...|...|.|
  Fly   265 PTPLYAM-----YDRDPSHNVQYQVQYWMNQTSEISVHKLHVGVTSYGRAWNM-TRNSGITGYPP 323

  Fly   300 ---AEGPGEQGDATREKGYLAYYEICQTLKDDPEWTVVQPNANVMGP-------YAYR------- 347
               |.|....|..|...|.|::.|||..|:..|:...| |:...:|.       ||||
  Fly   324 IPAANGAAPPGRQTVTPGLLSWPEICDLLQQQPQDREV-PHLRKVGDPTKRFGIYAYRAADDQGE 387

  Fly   348 RNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRGTCNGKPYPLIEAAK 401
            ...||||:|......||.:|.||||||:.|..:..|||||.|.|:.:|::.:.|
  Fly   388 NGLWVGYEDPLTAAIKAGFVHAQGLGGVAFHDLSMDDFRGQCAGEKFPILRSIK 441

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	111/407 (27%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	120/426 (28%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
Idgf5	NP_611321.3	GH18_IDGF	30..444	CDD:119352	120/427 (28%)
Idgf5	NP_611321.3	Glyco_18	30..423	CDD:214753	111/407 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910