DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht6 and Idgf3

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_001285982.1	Gene:	Idgf3 / 34981	FlyBaseID:	FBgn0020414	Length:	441	Species:	Drosophila melanogaster

Alignment Length:	450	Identity:	124/450 - (27%)
Similarity:	205/450 - (45%)	Gaps:	70/450 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 GAAWQTLFL-LCALAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYL--CTHLVYAFGG 68
            |:.|.:|.| |..||..  :.|:...:||:|.:....|.|.|:|:..:|...|  ||||||.:.|
  Fly     3 GSLWLSLALSLAVLAQF--KVSAAPNLVCFYDSQGSQRQGLAQFSMIDIELALQFCTHLVYGYAG 65

  Fly    69 FTKDN-QMKPFDKYQDIEQGGYAKFTGLKTYNKQLKTMIAIGG---WNEASSRFSPLVASNERRQ 129
            ...|| :|:..:|..|:||...|:.|.:|.....:|.::::||   ..|.:.....|.:..:..:
  Fly    66 VNADNYEMQSINKRLDLEQRHLAQITSMKERYPHIKFLLSVGGDADTYEGNQYIKLLESGQQGHR 130

  Fly   130 QFIKNILKFLRQNHFDGIDLDWEYP------AHREGGKSRDRDNYAQFVQELRAEF----EREAE 184
            :||::....:|:.:|||:||..:.|      .|.:.|.:     :..|.:....:|    |.|..
  Fly   131 RFIESARDLVRRYNFDGLDLALQLPRNKPRKVHGDVGSA-----WKSFKKFFTGDFIVDTESETH 190

  Fly   185 KTGRTR-------------LLLTMAVPAGIE---YIDKGYDVPKLNKYLDWFNVLTYDF--HSSH 231
            |...|.             |||::.|...:.   |    ||.|.:...||:.|:.|:||  ...:
  Fly   191 KGQVTALIKDLSAALKQNDLLLSLTVLPNVNSSWY----YDAPSIAPSLDFINLGTFDFLTPQRN 251

  Fly   232 EPSVNHHAPLYSLEEDSEYNYDAELNIDYSIKYYLKAGADRDKLVLGIPTYGRSYTLINEESTEL 296
            ....:..||.|   |....|.....|:::.::::|......:|:.:||.|||||:.: :::|.:.
  Fly   252 PEEADFSAPTY---EAVGQNRLGHYNLNFQMEHWLLQRVPANKINIGIATYGRSWKM-SKDSGDS 312

  Fly   297 GAP----AEGPGEQGDATREKGYLAYYEICQTLKDDPEWTVVQPNANV---------MGPYAYR- 347
            |.|    .:||...|..::::|.|.:.|||..:.:........|||.|         .|.||:|
  Fly   313 GMPVVPSTQGPAPAGPQSKQEGLLNWAEICSLMPNPSNSNARGPNAPVKRVVDPTKRYGSYAFRA 377

  Fly   348 ------RNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRGTCNGKPYPLIEAAK 401
                  ...|:.|||......||.|..|:.|||:..:.:..|||||.|....:|::.|.|
  Fly   378 ADENGDHGLWISYDDPDSASSKAMYARARNLGGVALFDLTQDDFRGQCTNDRFPMLRAIK 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	107/405 (26%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	115/423 (27%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
Idgf3	NP_001285982.1	GH18_IDGF	26..440	CDD:119352	115/424 (27%)
Idgf3	NP_001285982.1	Glyco_18	27..419	CDD:214753	107/404 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910