DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht6 and Idgf2

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_477257.2	Gene:	Idgf2 / 34979	FlyBaseID:	FBgn0020415	Length:	440	Species:	Drosophila melanogaster

Alignment Length:	449	Identity:	130/449 - (28%)
Similarity:	207/449 - (46%)	Gaps:	74/449 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 WQTLFLLCALAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYL------CTHLVYAFGG 68
            |.| |:.|..|.....||:   :||||.:.|..|.|..|.    :||.|      |:||||.:.|
  Fly     6 WFT-FVACLFAASTEAASN---LVCYYDSSSYTREGLGKL----LNPDLEIALQFCSHLVYGYAG 62

  Fly    69 FTKDN-QMKPFDKYQDIEQGGYAKFTGLKTYNKQLKTMIAIGGWNEAS----SRFSPLVASNERR 128
            ...:| |....::..||.:..:::.|.||.....||.::::||.::..    :::..|:...:.|
  Fly    63 LRGENLQAYSMNENLDIYKHQFSEVTSLKRKYPHLKVLLSVGGDHDIDPDHPNKYIDLLEGEKVR 127

  Fly   129 Q-QFIKNILKFLRQNHFDGIDLDWEYP------AHREGG---KSRDRDNYAQFVQELRAEFEREA 183
            | .||::....::...|||:||.:::|      .|.:.|   ||..:.....|:.:..|...:|
  Fly   128 QIGFIRSAYDLVKTYGFDGLDLAYQFPKNKPRKVHGDLGLAWKSIKKLFTGDFIVDPHAALHKE- 191

  Fly   184 EKTGRTR----------LLLTMAVPAGIE---YIDKGYDVPKLNKYLDWFNVLTYDF--HSSHEP 233
            :.|...|          .||::.|...:.   |    :|:|.||..:|:.|:.|:||  .:.:..
  Fly   192 QFTALVRDVKDSLRADGFLLSLTVLPNVNSTWY----FDIPALNGLVDFVNLATFDFLTPARNPE 252

  Fly   234 SVNHHAPLYSLEEDSEYNYDAELNIDYSIKYYLKAGADRDKLVLGIPTYGRSYTLINEESTELGA 298
            ..::.||:|  ..|...:..|.||.|:.::|:|..|...:|:.||:.|||.::.|..:...| |.
  Fly   253 EADYSAPIY--HPDGSKDRLAHLNADFQVEYWLSQGFPSNKINLGVATYGNAWKLTKDSGLE-GV 314

  Fly   299 P----AEGPGEQGDATREKGYLAYYEIC--------QTLK--DDPEWTVVQPNANVMGPYAYR-- 347
            |    ..||..:|..:::.|.|:|.|||        |.||  :.|...|..|... .|..|||
  Fly   315 PVVPETSGPAPEGFQSQKPGLLSYAEICGKLSNPQNQFLKGNESPLRRVSDPTKR-FGGIAYRPV 378

  Fly   348 -----RNQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDNDDFRGTCNGKPYPLIEAAK 401
                 ...||.|||......||.|...:.|||:..:.:..|||||.|:|..||::.|.|
  Fly   379 DGQITEGIWVSYDDPDSASNKAAYARVKNLGGVALFDLSYDDFRGQCSGDKYPILRAIK 437

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	112/408 (27%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	123/427 (29%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
Idgf2	NP_477257.2	GH18_IDGF	23..440	CDD:119352	123/431 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.910