DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht6 and chil-25

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_001300596.1	Gene:	chil-25 / 188614	WormBaseID:	WBGene00011846	Length:	483	Species:	Caenorhabditis elegans

Alignment Length:	417	Identity:	118/417 - (28%)
Similarity:	178/417 - (42%)	Gaps:	104/417 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 RVVCYYTNWSVYRPGTAKFNPQNINPYLCTHLVYAFGGFTKDNQMKPFDKYQDIEQGGYAKFTGL 95
            |||.||:     |..|:|.....::.  .||.|:||.....|..:| |:| ||.|.    :|..|
Worm   110 RVVGYYS-----RSETSKITSVQVSK--LTHAVFAFVYMNSDGTLK-FEK-QDEED----RFMQL 161

  Fly    96 KTY----NKQLKTMIAIGGWNEASSRFSPLVASNERRQQFIKNILKFLRQNHFDGIDLDWEYPAH 156
            |..    ...:|.||:||| .|.|..|||::.|..|||.||.:||.||::|..|||||.||:|.
Worm   162 KDIVNMGTSPVKIMISIGG-KENSQNFSPVIESEYRRQIFINSILTFLKENDLDGIDLFWEWPC- 224

  Fly   157 REGGKSRDRDNYAQFVQELRAEFEREAEKTGRTRLLLTMAVP----AGIEYIDKGYDVPKLNKYL 217
                 |..:..|..|:.||:.:.:     |.....:|::.||    .|  :|| |:|:..:.:.:
Worm   225 -----STYKSVYLHFICELKQQLQ-----TKDKDYILSIVVPPPEVGG--WID-GFDMNNIVQIV 276

  Fly   218 DWFNVLTYDFHSSHEPSVNHH-------APLYSLEEDSEYNYDAELNIDYSIKYYLKAGADRDKL 275
            |:.||.:.|::.   |:.|..       ||:::.....|     ..|:|::.|.........:|.
Worm   277 DFINVFSLDYYG---PTQNDFGKITGPTAPMFNGVPGRE-----TFNVDHTSKVLSCETMQSNKF 333

  Fly   276 VLGIPTYGRSYTLINEESTELGAPAEGPGEQGDATREKGYLAYYEICQTLKDDPEWTVVQPNANV 340
            .:.||.|           |.|....:||.::.:..|....:....:.|:   .....:||....|
Worm   334 NIAIPFY-----------TTLWENVQGPIDKIEIFRNVNKVHGKIVGQS---HMSRMIVQQKGFV 384

  Fly   341 MGPYAY---RRNQWVGYD-----------DEAIVRKKAEYVVAQGLGGIMFWAIDNDD------- 384
            :.||::   .||.:: |:           |::|| .|.|||....||||..|.:|.||
Worm   385 LTPYSFDNATRNAFI-YNSSTKIYLTFETDQSIV-AKIEYVSEHLLGGICIWTVDKDDEGNSQLN 447

  Fly   385 ---FRGTC-------------NGKPYP 395
               |.|.|             ||...|
Worm   448 AISFDGLCTTGNVPKYDCSYWNGNTLP 474

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	110/380 (29%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	117/416 (28%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
chil-25	NP_001300596.1	Glyco_18	110..439	CDD:214753	110/380 (29%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.810