DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht6 and lmd-5

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_001309512.1	Gene:	lmd-5 / 187942	WormBaseID:	WBGene00020141	Length:	1518	Species:	Caenorhabditis elegans

Alignment Length:	409	Identity:	111/409 - (27%)
Similarity:	186/409 - (45%)	Gaps:	79/409 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 ASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYLCTHLVYAFGGFTKDNQMKPFDKYQDIEQGGYA 90
            ||...|:|.|||.|     |..:.....:..  .||:::||.....|..:| |......:.|..|
Worm   986 ASCGKRIVGYYTGW-----GEREITENQLKK--LTHVIFAFVAMYADGSVK-FGPVSADDPGPQA 1042

  Fly    91 ------KFTGLK----TYNKQLKTMIAIGGWNEASSRFSPLVASNERRQQFIKNILKFLRQNHFD 145
                  :|..:|    ..|..::.:.|:|||:. |..||.:.|.:.:|:.|:.::..|:..:..|
Worm  1043 GKKAERRFVDMKKKARAVNSGVRVLFAVGGWDN-SQYFSSVAADSGKRRNFVDSVASFIEHHKID 1106

  Fly   146 GIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREAEKTGR-TRLLLTMAVPAGIEYIDKGYD 209
            |:|||||||..:.|    |:.|:...::|||..|...|.:..| ...|:|:|..||...:.:|||
Worm  1107 GVDLDWEYPEMKGG----DKQNHVTLIRELRERFNGMASRNNRKDPYLITLASAAGEWNLREGYD 1167

  Fly   210 VPKLNKYLDWFNVLTYDFHSSHEPSVNHH----APLY--SLEEDSEYNYDAELNIDYSIKYYLKA 268
            :..:..|.|:.||:|||::.:.|.....:    ||||  ||:     .:..:||.|:|:|:|...
Worm  1168 LKGILNYADFINVMTYDYYGAWESKWGAYTGTPAPLYFGSLK-----GFSGKLNADFSMKFYACN 1227

  Fly   269 GADRDKLVLGIPTYGRSYTLI------NEESTELGAPAEGPGEQG-----DATRE---KGYLAYY 319
            .....:|.:|:|.|||.:..:      ::......||..|..|.|     :..:|   ||...::
Worm  1228 TKKPSQLTMGVPFYGRYWKNVLEPIDASDNMWRTAAPQNGKYEGGYVGWRNLEKEGWNKGSATWH 1292

  Fly   320 EICQTLKDDPEWTVVQPNANVMGPYAYRR--NQWVGYDDEAIVRKKAEYVVAQGLGGIMFWAIDN 382
            :..:|                  ||....  ..::|:::|..:::|.:|...:.|||:|.||:|.
Worm  1293 KKTKT------------------PYIMNNGARMFLGFENERSLKEKMDYATNRNLGGLMIWALDL 1339

  Fly   383 DD----------FRGTCNG 391
            ||          ..|.|:|
Worm  1340 DDDADTLLNLVSSAGLCSG 1358

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	104/384 (27%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	108/403 (27%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
lmd-5	NP_001309512.1	LysM	22..65	CDD:197609
		LysM	77..120	CDD:197609
		LysM	151..194	CDD:197609
		LysM	220..260	CDD:197609
		LysM	275..312	CDD:197609
		LysM	386..429	CDD:197609
		Self-incomp_S1	851..944	CDD:283566
		Glyco_18	991..1336	CDD:214753	101/380 (27%)
		GH18_chitinase-like	992..1336	CDD:299167	100/379 (26%)
		ChtBD1_GH18_2	1388..1435	CDD:211315
		ChtBD1_GH18_2	1462..1513	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820