DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Cht6 and chil-8

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_001379090.1	Gene:	chil-8 / 174541	WormBaseID:	WBGene00007473	Length:	399	Species:	Caenorhabditis elegans

Alignment Length:	403	Identity:	87/403 - (21%)
Similarity:	186/403 - (46%)	Gaps:	70/403 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFLLCALAYCINEASSEGRVVCYYTNWSVYRPGTAKFNPQNINPYL---------------CTHL 62
            ||:...:::.::.      :.||:.::|......:..:.:.|..|:               .||:
Worm    15 LFVFGIVSFLVSS------LFCYFYDFSNSVQSPSVLHRKRIIGYVSSDEGSEITIKQLEKLTHV 73

  Fly    63 VYAFGGFTKDNQMKPFDKYQDIEQGGYAKFTGLK----TYNKQLKTMIAIGGWNEASSRFSPLVA 123
            ::||....||..:|       .:.|....|..:|    ..|:.||.|::|||: |:|..||.::.
Worm    74 IFAFILVHKDGTIK-------FKYGTKDGFFDMKRKSMELNRGLKVMVSIGGY-ESSPLFSDVLV 130

  Fly   124 SNERRQQFIKNILKFLRQNHFDGIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREAEKTGR 188
              :::::.|.:|...:::...||:|:.|.:|:      ..|:.||..|::|||.:.....::.||
Worm   131 --KKKKKLIASIALLVKKFDLDGVDIFWNWPS------ITDQSNYLIFIRELRKKLTNLKDENGR 187

  Fly   189 T-RLLLTMAVPAGIEYIDKGYDVPKLNKYLDWFNVLTYD-FHSSHEPSVNHHAPLYSLEEDSEYN 251
            : ..::::..|:...:.:..|...::.:.:|:.||:|:: |:.:::  :..|:|||.    ..:.
Worm   188 SNEYVISVIAPSSSSHSEYPYKWTEILENVDFINVITFEYFYEANK--IGPHSPLYG----GSFG 246

  Fly   252 YDAELNIDYSIKYYLKAGADRDKLVLGIPTYGRSYTLINEESTELGAPAEG---PGEQGDATREK 313
                 |:|.::||.:......:||.:.:     |:..|...:|.|....:|   |.:........
Worm   247 -----NVDDTLKYLICRTRTPNKLNMVV-----SFNGIYWGNTTLPFDDKGVWIPDDSAQGPYSY 301

  Fly   314 GYLAYYEICQTL-KDDPEWTVVQPNANVMGPYAYRRN--QWVGYDDEAIVRKKAEYVVAQGLGGI 375
            |:..:..:.... ::|.||     |.....||.::.:  |::.:::|..:.:|..|.||..:||:
Worm   302 GWKQFARMSHGFDQNDFEW-----NEETRTPYIWKADTQQFLTFENEKSLTEKMNYAVAHNIGGV 361

  Fly   376 MFWAIDNDDFRGT 388
            ..:.||:||...|
Worm   362 AMYTIDDDDEENT 374

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	82/378 (22%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	85/384 (22%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
chil-8	NP_001379090.1	Glyco_18	49..369	CDD:214753	79/356 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1289629at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820