DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Cht6 and chil-13

DIOPT Version :9

Sequence 1:	NP_001245598.1	Gene:	Cht6 / 31935	FlyBaseID:	FBgn0263132	Length:	4611	Species:	Drosophila melanogaster
Sequence 2:	NP_496018.2	Gene:	chil-13 / 174500	WormBaseID:	WBGene00010945	Length:	439	Species:	Caenorhabditis elegans

Alignment Length:	413	Identity:	98/413 - (23%)
Similarity:	186/413 - (45%)	Gaps:	82/413 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LFLLCAL-------AYC----------INEAS-----SEGRVVCYYTNWSVYRPGTAKFNPQNIN 55
            :.::|.|       .||          :|..|     .:.|:|.|::...     :.:.:...|:
Worm    41 VLMICGLIAFGITEIYCRLFPVTDNLVLNNESPKKPVCKRRIVGYFSEIE-----STEISKSQID 100

  Fly    56 PYLCTHLVYAFGGFTKDNQMKPFDKYQDIEQGGYAKFTGL--KTYNKQLKTMIAIGGWNEASSRF 118
            .  .||.|:||.....|..::..:...|:      :|:.|  ||....::.|::|||..|.:..|
Worm   101 K--LTHAVFAFVRIKYDGTLQFDNSKADL------RFSILKDKTRGSNVEMMVSIGGGYENAHYF 157

  Fly   119 SPLVASNERRQQFIKNILKFLRQNHFDGIDLDWEYPAHREGGKSRDRDNYAQFVQELRAEFEREA 183
            :..::.:::::.||.:||.||.::..||:|..|::|.      .:|..||..|::|||    ::.
Worm   158 ASALSDSQKKKNFIDSILAFLVEHRIDGVDFFWQWPT------VQDTFNYVTFIRELR----QKL 212

  Fly   184 EKTGRTRLLLTMAVP-AGIEYIDKGYDVPKLNKYLDWFNVLTYDFHSSHEPSVNH-------HAP 240
            ::..|...|::|.|| ||::..:.|:|:.:|..::|:|||.:.|:..   |..|.       .:|
Worm   213 DENKRKHFLISMTVPAAGVDNWELGFDLEELQNHVDFFNVYSMDYAG---PWPNQWGVPTGPSSP 274

  Fly   241 LYSLEEDSEYNYDAELN--IDYSIKYYLKAGADRDKLVLGIPTYGRSYTLINE---ESTELGAPA 300
            ::       ||..|..|  :|:::|:|.........|.:.||...|.:..:.|   ..||:...|
Worm   275 MF-------YNIGARKNFYVDWTMKHYTCKLKQPSMLNMVIPFSARIWNNVQEAIDNRTEVFRNA 332

  Fly   301 EGPGEQGDA-TREKGYLAYYEICQTLKDDP-EWTVVQPNANVMGPYA--YRRNQWVGYDDEAIVR 361
            |......:. |:...:.|.:|   .|:..| .|..:     .|.||.  .:...::.::|:..::
Worm   333 ELKNNMAEGRTQISRWTAEHE---GLELSPSSWDNL-----TMTPYILDLKAKTFLTFEDKRSIK 389

  Fly   362 KKAEYVVAQGLGGIMFWAIDNDD 384
            .|.:|.....|||:..|::|.||
Worm   390 IKTDYAKKMDLGGVWLWSVDMDD 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Cht6	NP_001245598.1	Glyco_18	31..383	CDD:214753	90/370 (24%)
		GH18_chitolectin_chitotriosidase	32..404	CDD:119351	91/372 (24%)
		CBM_14	506..562	CDD:279884
		Oxidored_q2	<2691..2750	CDD:294335
		CBM_14	4554..4609	CDD:279884
chil-13	NP_496018.2	Glyco_18	81..411	CDD:214753	90/370 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D264489at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm4747
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.820