DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG2990 and AT2G03270

DIOPT Version :9

Sequence 1:	NP_727386.1	Gene:	CG2990 / 31934	FlyBaseID:	FBgn0030170	Length:	1100	Species:	Drosophila melanogaster
Sequence 2:	NP_565299.1	Gene:	AT2G03270 / 814856	AraportID:	AT2G03270	Length:	639	Species:	Arabidopsis thaliana

Alignment Length:	702	Identity:	175/702 - (24%)
Similarity:	294/702 - (41%)	Gaps:	167/702 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   450 AYVQHWCGLLALEEQHNRQSSHVRSFWTKDPAEREKEGIAIRHLKLVKGQEVILEEGRYRQTLEL 514
            |:|.....|:.:|::.....| :.|..:::....:|:|..|.:||.|..|..::.:.........
plant     9 AFVSTMAPLIDMEKEAEISMS-LTSGASRNIETAQKKGTTILNLKCVDVQTGLMGKSLIEFQSNK 72

  Fly   515 GEEADPSRD--------LSLSGFDLGEYVVISSTSRLAVAAGFI--------------VSIEARR 557
            |:.. |:..        |.|:..|||     ||    .:|.|.:              |..|...
plant    73 GDVL-PAHKFGNHDVVVLKLNKSDLG-----SS----PLAQGVVYRLKDSSITVVFDEVPEEGLN 127

  Fly   558 LDLRLER---DLSQRYSEETFIIDKHDSQSFATFNFTNLGMLLSEGERFQELRDIIVAKKPPEQH 619
            ..||||:   :::.|..::|.|                   .||:|.......|::.......|.
plant   128 TSLRLEKLANEVTYRRMKDTLI-------------------QLSKGVLRGPASDLVPVLFGERQP 173

  Fly   620 KVLPKIILTKGAPILLNLNKVQQNAALRALTTSSHLLIKGLPGTGKTQTLVALVRLLHLLGKSVL 684
            .|..|.: ....|...||::.|::|..:||::....|:.|.||||||.|:|.:|......|..:|
plant   174 SVSKKDV-KSFTPFNKNLDQSQKDAITKALSSKDVFLLHGPPGTGKTTTVVEIVLQEVKRGSKIL 237

  Fly   685 ITAQTHSAVDNLIMRLLPFGLPMMRLGSGSR-------------------------IHKQLEEIS 724
            ..|.::.||||::.||:|..:.::|:|..:|                         |.|:::.::
plant   238 ACAASNIAVDNIVERLVPHKVKLVRVGHPARLLPQVLDSALDAQVLKGDNSGLANDIRKEMKALN 302

  Fly   725 EERL-TKDCKTVEELEK---ALGQ----------------PSIVGVTCLGCGHPLFQRRQFDYCI 769
            .:.| .||..|...::|   .||:                ..::..|..|........|.||..|
plant   303 GKLLKAKDKNTRRLIQKELRTLGKEERKRQQLAVSDVIKNADVILTTLTGALTRKLDNRTFDLVI 367

  Fly   770 VDEATQVLQPTVLRPLIHCSKFVLVGDPEQLPPIVRSKEARQRGADETLFQRLD---SEKATAVL 831
            :||..|.|:......|:..|:.:|.||..||||.::|.||.::|...|||:||.   .::..::|
plant   368 IDEGAQALEVACWIALLKGSRCILAGDHLQLPPTIQSAEAERKGLGRTLFERLADLYGDEIKSML 432

  Fly   832 SLQYRMNKTITRLANELTYGGDLKCASDEVSGARFEVELLNEAPRWVQRALTTHLEQAVTLINTG 896
            ::||||::.|...:::..|...:...|...|...|::|.:.:         ::..|..:.|::|.
plant   433 TVQYRMHELIMNWSSKELYDNKITAHSSVASHMLFDLENVTK---------SSSTEATLLLVDTA 488

  Fly   897 DCLERCQEFVYASQRLVDTCSSIEQSFSEDKDEIRKLTSKKRVSKYTNYCEAGIVMHLLRYLLKS 961
            .|                       ...|.|||        ..|.| |..||.:.|...:.|::|
plant   489 GC-----------------------DMEEKKDE--------EESTY-NEGEAEVAMAHAKRLMES 521

  Fly   962 GYEASRIGVIAPYRAQVELFKKLASKLD--TDLECNTVDQFQGRDKNLIIYSCSKTGGDFSDMER 1024
            |.:.|.||:|.||.|||.|.:.|..|.:  .|:|.:|||.||||:|..||.|..::..
plant   522 GVQPSDIGIITPYAAQVMLLRILRGKEEKLKDMEISTVDGFQGREKEAIIISMVRSNS------- 579

  Fly  1025 SREAEILEDQRRLTVAITRAKNKLILLGD-------------IKCLEQYGPF 1063
            .:|...|:||||:.||:||::.:..::.|             |:..|::|.:
plant   580 KKEVGFLKDQRRMNVAVTRSRRQCCIVCDTETVSSDAFLKRMIEYFEEHGEY 631

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2990	NP_727386.1	Dna2	99..297	CDD:285859
		Cas4_I-A_I-B_I-C_I-D_II-B	<283..415	CDD:294426
		TIGR00376	480..1069	CDD:273041	169/672 (25%)
		P-loop_NTPase	636..859	CDD:304359	74/270 (27%)
		AAA_12	815..1055	CDD:289832	69/257 (27%)
AT2G03270	NP_565299.1	TIGR00376	20..636	CDD:273041	172/691 (25%)
		AAA_19	196..>253	CDD:289986	21/56 (38%)
		AAA_12	412..610	CDD:289832	69/245 (28%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG1112
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D633768at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820