Protein Alignment CG2990 and Mov10l1

DIOPT Version :9

• Sequence 1: NP_727386.1
• Gene: CG2990 / 31934
• FlyBaseID: FBgn0030170
• Length: 1100
• Species: Drosophila melanogaster
• Sequence 2: XP_017450774.2
• Gene: Mov10l1 / 300141
• RGDID: 1304735
• Length: 1291
• Species: Rattus norvegicus
• Alignment Length: 1201
• Identity: 253/1201 - (21%)
• Similarity: 391/1201 - (32%)
• Gaps: 446/1201 - (37%)

  Fly   186 GTLVHELLQ-KVLRQKLFDKKHIQSALQEMLASSSLAHLLYASNLIQVEMEDHLMKFIDPIVSFV 249
            ||...|.:. |.||.|..||..|.|              |...|.:   :||.:...:|
  Rat   167 GTWSSEAISVKPLRYKRVDKVCISS--------------LCGRNGV---IEDSIFFSLD------ 208

  Fly   250 AQYVKGEPPSVLLPEVYRGQIHEICD---IEEN----LW----------------VPQ-----LG 286
                     |:.|||.|..:.|:|.:   :|.:    :|                .||     |.
  Rat   209 ---------SLKLPEGYTPRRHDIVNAVVVESSQSCYIWRALCMTPVKREAIIGEAPQEPYGALL 264

  Fly   287 LKGKVDVSV-------KVKNQRQREEIIPLELKTGRAS---FSMEHKGQLLLYQLMHSAQGR-DT 340
            ||.|.||.|       .:|....:..:|.:|.| |..|   .|....|....:|....|||| ..
  Rat   265 LKNKGDVEVTRTTSFGTLKEGESKAVVIWIENK-GEISQDLVSCRLAGWDKAHQFRFEAQGRGQA 328

  Fly   341 QSGL-LLYLKEGLLREVASGRNEQRD-------LLMLRND--------LAYWLTREVAIPASKED 389
            .:|: .:.:.||   |..:..|..|:       ...|.|:        .....:||....|.|::
  Rat   329 CAGVAAVAVSEG---ENVNSLNHHREDKPDPIPESSLENNTEISPDGCACTEESREKGDTAEKQE 390

  Fly   390 PLE--QLPLPEPVYHHSAC-----GNC-------------------------------------- 409
            |..  .:|..|.......|     |.|
  Rat   391 PEPGGLIPPGEKTSIVVTCNAKNPGRCKELLLLCFSNFLIGRHLEVNVVSSEEALIAVREPFSWK 455

  Fly   410 ----------AYNTICSSFAQKDSSLQLSDSHP-------LKK----------LMPQLLEHLSEA 447
                      |..|:..:..:::|..||....|       |||          ..|.|.|.|:.:
  Rat   456 KPKSSQTIVSAKTTVVVTTQKRNSRRQLPSFLPQYPIPDRLKKCVEQKIDILTFQPLLAELLNMS 520

  Fly   448 DHAYVQHWCGLLALEEQH---NRQSSHVRSFWTKDPAE---REKEGIAIRHLKLVKGQEVILEEG 506
            :  |.:.:..||.|||.|   ..:..::.....|...|   .|..|:|.....|..|.::||:..
  Rat   521 N--YKEKFSTLLWLEEIHAEIELKEYNMSGVVLKRKGELLVLEVPGLAESRPSLYAGDKLILKSQ 583

  Fly   507 RYR--------QTLELGEEADPSRDLSLS---GFDL--------GEYVVISSTSR---------- 542
            .|.        ..:|:.||     |::|.   ||:.        .|:....:|||
  Rat   584 EYNGHVIEYIGYVMEIHEE-----DVTLKLNPGFEQMYNFEPMDVEFTYNRTTSRRCHYALEQVI 643

  Fly   543 -LAVAAGFIVSI-------------------------EARRLDLRLERDLSQRYSEETFIIDKHD 581
             |.|...|...|                         :..|.|.:...::::...:....|.|:|
  Rat   644 HLGVKVLFPEEIILQSPQVTGNWSLAQDTKSDGQSITKVTRNDGQSITNITKNDGQSITNITKND 708

  Fly   582 SQSFATF------NFTNL---------------GMLLSEGER--FQELRDII------VAKKPPE 617
            .||....      :.||:               |..:::..|  .|.:.:|.      :.|....
  Rat   709 GQSITKVTKNDGQSITNITKNDGQSITSITKNGGQSINKVTRNDGQSITNITRNDGQSITKVTKN 773

  Fly   618 QHKVLPKIILTKGAPILLN---------------------------------------------- 636
            ..:.:.|:....|..|..|
  Rat   774 GGQSISKVTRNDGQSITKNKKTVKDQTKNTTKERHLSTTDQPEKTASTAETMDEIQIPRARDKEF 838

  Fly   637 ----LNKVQQNAALRALTTSSH---LLIKGLPGTGKTQTLVALVRLLH--LLGKSVLITAQTHSA 692
                ||:.|:.|..|.|:....   .::.|.||||||.|::..|..:|  |....:|:.|.::||
  Rat   839 FNPVLNENQKLAVRRILSGDCRPLPYILFGPPGTGKTVTIIEAVLQVHYALPDSRILVCAPSNSA 903

  Fly   693 VDNLIMRLLPFGL----PMMRLGSGSRIHKQLEEISEERLTKDCKTVEELEKALGQPSIVGVTCL 753
            .|.:.:||....:    .|:|:.:..|    .||...|.:...|:..|::.:| .:..|:..||.
  Rat   904 ADLVCLRLHESKVLKPAAMVRVNATCR----FEETIIEAIKPYCRDGEDIWRA-SRFRIIITTCS 963

  Fly   754 GCGHPLFQR-----RQFDYCIVDEATQVLQPTVLRPLIHCS----KFVLVGDPEQLPPIVRSKEA 809
            ..|  ||.:     ..|.:..||||.|..:|..|.||...|    :.||.|||.||.|:::|:.|
  Rat   964 SAG--LFYQIGVRVGYFTHVFVDEAGQASEPECLIPLGLISDINGQIVLAGDPMQLGPVIKSRLA 1026

  Fly   810 RQRGADETLFQRLDSEKA--------------------------TAVLSLQYRMNKTITRLANEL 848
            ...|.:.::.:||.|..|                          ...|...||.:..:..|.:.|
  Rat  1027 MAYGLNVSMLERLMSRPAYLRDENAFGACGAYNPLLPLPASSPQVTKLVKNYRSHSALLALPSRL 1091

  Fly   849 TYGGDLK-CASDEVSGARFEVELL--------------NEA-----PRWVQRALTTHLEQAVTLI 893
            .|..:|: ||..:|..:....|.|              |||     |.|...|      :||.::
  Rat  1092 FYHRELEVCADPKVVTSLLGWEKLPRKGFPLIFHGVRGNEAREGRSPSWFSPA------EAVQVM 1150

  Fly   894 NTGDCLERCQEFVYASQRLVDTCSSIEQSFSEDKDEIRKLTSKKRVSKYTNYCEAGIVMHLLRYL 958
                                                              .||      .||...
  Rat  1151 --------------------------------------------------RYC------CLLARN 1159

  Fly   959 LKSGYEASRIGVIAPYRAQVELFKKLASKLD-TDLECNTVDQFQGRDKNLIIYSCSKTGGDFSDM 1022
            :.|...:..||||.|||.|||..|.|...:| ||::..:|::|||::..:|:.|..::..|..:.
  Rat  1160 VSSQVSSKDIGVITPYRKQVEKIKILLRNVDLTDIKVGSVEEFQGQEYLVIVISTVRSNEDRFED 1224

  Fly  1023 ERSREAEILEDQRRLTVAITRAKNKLILLGD 1053
            :| .....|.:.:|..|||||.|..||:||:
  Rat  1225 DR-YFLGFLSNSKRFNVAITRPKALLIVLGN 1254

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2990	NP_727386.1	Dna2	99..297	CDD:285859	34/146 (23%)
		Cas4_I-A_I-B_I-C_I-D_II-B	<283..415	CDD:294426	42/218 (19%)
		TIGR00376	480..1069	CDD:273041	167/776 (22%)
		P-loop_NTPase	636..859	CDD:304359	75/317 (24%)
		AAA_12	815..1055	CDD:289832	64/286 (22%)
Mov10l1	XP_017450774.2	PRK08581	657..>833	CDD:236304	18/175 (10%)
		DEXXQc_Mov10L1	842..1079	CDD:350836	66/243 (27%)
		SF1_C_Upf1	1080..1270	CDD:350195	57/238 (24%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910