DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG2990 and LOC100360296

DIOPT Version :9

Sequence 1:	NP_727386.1	Gene:	CG2990 / 31934	FlyBaseID:	FBgn0030170	Length:	1100	Species:	Drosophila melanogaster
Sequence 2:	XP_008771545.2	Gene:	LOC100360296 / 100360296	RGDID:	2322455	Length:	239	Species:	Rattus norvegicus

Alignment Length:	186	Identity:	32/186 - (17%)
Similarity:	72/186 - (38%)	Gaps:	51/186 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly   493 LKLVKGQEV--ILEEGRYRQTLELGEEADPSRDLSLSGFDLGEYVVISSTSRLAVAAGFIVSIEA 555
            |.||:..||  .|:..:.:...:|.|.::||:        ||:        ||.:.....|:.|
  Rat    73 LALVEQDEVTHTLKTIKVKVMTDLPEGSEPSK--------LGK--------RLCIRCVTSVTEE- 120

  Fly   556 RRLDLRLERDLS----------QRYSEETFIIDKHDSQSFATFNFTNLGMLLSEGERFQELRDII 610
               |:.:..|:|          :.:..:..:::...:...:..|..::..|     ..|::.::.
  Rat   121 ---DVYISEDVSFPLYLFSGAFKPFKGDLVLVEYSMNSGMSNINIHSVSPL-----SCQDINEVY 177

  Fly   611 VAKKPPEQHKVLPKIILTKGA--------PIL------LNLNKVQQNAALRALTTS 652
            |.........|..::..|..:        |.|      :.::.:||:.:|||::.:
  Rat   178 VTSIDGRNGMVEARVFFTLDSLQIPSGYTPGLYDIVDVVTVDSIQQHCSLRAVSVT 233

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG2990	NP_727386.1	Dna2	99..297	CDD:285859
		Cas4_I-A_I-B_I-C_I-D_II-B	<283..415	CDD:294426
		TIGR00376	480..1069	CDD:273041	32/186 (17%)
		P-loop_NTPase	636..859	CDD:304359	5/17 (29%)
		AAA_12	815..1055	CDD:289832
LOC100360296	XP_008771545.2	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166335121
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930