Protein Alignment CG2990 and setx

DIOPT Version :9

• Sequence 1: NP_727386.1
• Gene: CG2990 / 31934
• FlyBaseID: FBgn0030170
• Length: 1100
• Species: Drosophila melanogaster
• Sequence 2: XP_002936221.1
• Gene: setx / 100145435
• XenbaseID: XB-GENE-966858
• Length: 2535
• Species: Xenopus tropicalis
• Alignment Length: 1016
• Identity: 238/1016 - (23%)
• Similarity: 372/1016 - (36%)
• Gaps: 332/1016 - (32%)

  Fly   236 DHLMKFIDPIVSFVAQYVK-GEPPSVLLPEVYR-------GQIHEICDIEENLWVPQLGLKGKVD 292
            ||..|.:.|..:....:.| |.||||..|...:       .:...:....||...|| |:
 Frog  1472 DHCPKHMPPEKADDHLFAKPGLPPSVSKPSTTKVFASSNTSRTASLTKDLENFPRPQ-GI----- 1530

  Fly   293 VSVKVKNQRQREEI--IPLELKTGRASFSMEHKGQLLLYQLMHSAQGRDTQSGLLLYLKEGLLRE 355
              :|.|.|..:..:  :|..|.....:.......|.|:.|  .:...:.:.|.:   .:.|.||.
 Frog  1531 --LKAKPQSAKAPVPKLPKPLTVQNRASDTNSVLQPLINQ--SNVPSKPSYSAV---SEAGKLRP 1588

  Fly   356 VASGRN-EQRDLLMLRNDLAYWLTREVAIPASKEDP---LEQLPLPE-PV-------YHHSACGN 408
            .|:.:. :|||...|..:|..| ..|:....|:..|   |.||||.: |:       |.:.....
 Frog  1589 YAAQKPLQQRDQGWLMRELLQW-KFEMFDNVSRFGPPSNLCQLPLLKVPIKFSSYEEYFNVFFPL 1652

  Fly   409 CAYNTICSSFAQKDSSLQLSDSHPLKKLMPQLLEHLSEADHAYVQHWC--GLLALEEQHNRQSSH 471
            ...||. .|.||:.|..|.:....|.||              ::|::|  ||:      ||....
 Frog  1653 MLLNTF-ESLAQEWSVKQKAIHTDLCKL--------------HLQNFCPDGLV------NRGEFQ 1696

  Fly   472 VRSFWTKDPAEREKEGIAIRHLKLVKGQEVILEEGRYRQTLELGEEAD------PSRDLSLSGFD 530
            |   |.:|     .:....||.|                      |.|      |....||||.:
 Frog  1697 V---WFRD-----ADLCMQRHPK----------------------EDDLVFLCMPESTPSLSGEE 1731

  Fly   531 LGEYVVISSTSRLAVAAGFIVSIEARRLDLRLERDLSQRYSEETFI-IDKHDSQSFATFNFTN-- 592
            :     :|..:|: ...|::....      |..|..||...:.|.. :..|...:.:.|....
 Frog  1732 M-----VSHGARV-YHTGYVSRFN------RSHRTQSQEKEQYTLCDLCIHTQGNLSAFRNQQVR 1784

  Fly   593 ---LGMLLSEGERFQELRDIIVAKKPPEQHKVLPKIILTKGA---------------PILLNLNK 639
               :|.|::...:|:.|..:       :::.:...|||...|               |.|...|.
 Frog  1785 CAVIGSLITTQRQFRALLQL-------QRNPLFRPIILPNPADFIPRDNAASESSSFPSLKEYNS 1842

  Fly   640 VQQNAALRALT-TSSH------LLIKGLPGTGKTQTLVALV-RLLHLLGKS-------------- 682
            .|:.|..:|.: ...|      .||.|.|||||::|:|.|: |:|...|.|
 Frog  1843 DQRYAIEKAYSMVKQHPRLPRICLIHGPPGTGKSKTIVGLLYRILMENGSSTVPVQNLSAKNKRN 1907

  Fly   683 -VLITAQTHSAVDNLIMRLL------------PFG----LPMMRLGS------------------ 712
             ||:.|.:::|:|:|:.:::            |.|    :.::|||:
 Frog  1908 RVLVCAPSNAALDDLMKKIILEFKEKCHNKNTPLGNCGDINLVRLGAEKTISSDVVKFSLDCQVN 1972

  Fly   713 --------GSRIHK-------QLEEISEERLTKDC------------------------------ 732
                    ...:||       :|:|:|..|..:.|
 Frog  1973 HRITRAQQDQELHKRKELLDRRLDELSRRRALEKCNKNTCAPLDEEIARLSKERQLLADSLKLVR 2037

  Fly   733 KTVEELEKALGQPS-IVGVTCLGCGHPLFQ-------RRQFDYCIVDEATQVLQPTVLRPLIH-C 788
            :..:||::.:...| ::..|....|..|.:       :..|...|||||.|..:...|.||:| |
 Frog  2038 RRPQELQRTIILESHVICCTLSTSGGILLESAFRQLGQEPFSCVIVDEAGQSCEVENLIPLLHRC 2102

  Fly   789 SKFVLVGDPEQLPPIVRSKEARQRGADETLFQR----LDS---EKATAVLSLQYRMNKTITRLAN 846
            ||.|||||||||||.|.|.:|.:.|..::|..|    |||   :.....|::||||:..|....:
 Frog  2103 SKLVLVGDPEQLPPTVISMKAEELGYGQSLMSRMCSFLDSTGTKSPVLHLTVQYRMHPDICLFPS 2167

  Fly   847 ELTYGGDLKC--ASDEVSGARFEVELLNEAPRWVQRALTTHLEQAVTLINTGDCLERC-QEFVYA 908
            ...|...||.  |::||                                       || .::.:.
 Frog  2168 HYFYKRMLKTDRATEEV---------------------------------------RCSSDWPFQ 2193

  Fly   909 SQRLVDTCSSIEQSFSEDKDEIRKLTSKKRVSKYTNYCEAGIVMHLLRYLLKSGYEA---SRIGV 970
            ...:.|.....||              |:|.| :.|..|..:.:.|:: |:||..:.   ..|||
 Frog  2194 PYMVFDVADGFEQ--------------KERES-FCNPQEIKVAVALIK-LIKSRKKEFCFRNIGV 2242

  Fly   971 IAPYRAQ-VELFKKLASKLDTDL---ECNTVDQFQGRDKNLIIYSC----SKTGGDFSDMERSRE 1027
            |.||||| :.:.::|......|:   |.:|||.||||.|:.||.:|    |..||
 Frog  2243 ITPYRAQKMRIIEELRRAFGNDIRPGEVDTVDGFQGRQKDCIIVTCVRANSTQGG---------- 2297

  Fly  1028 AEILEDQRRLTVAITRAKNKLILLGDIKCLEQYGPFRQLFK 1068
            ...|..::||.|.|||||..|.:||.::.|.:...:..|.:
 Frog  2298 IGFLASRQRLNVTITRAKFSLFILGSLRTLMENKDWNHLIQ 2338

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG2990	NP_727386.1	Dna2	99..297	CDD:285859	16/68 (24%)
		Cas4_I-A_I-B_I-C_I-D_II-B	<283..415	CDD:294426	34/145 (23%)
		TIGR00376	480..1069	CDD:273041	174/748 (23%)
		P-loop_NTPase	636..859	CDD:304359	88/342 (26%)
		AAA_12	815..1055	CDD:289832	69/260 (27%)
setx	XP_002936221.1	DEXXQc_SETX	1840..2157	CDD:350800	80/316 (25%)
		AAA_12	2128..2323	CDD:404073	68/259 (26%)
		PHA03247	<2365..2534	CDD:223021

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910