Protein Alignment CG1889 and ANGPTL1

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_004664.1
• Gene: ANGPTL1 / 9068
• HGNCID: 489
• Length: 491
• Species: Homo sapiens
• Alignment Length: 329
• Identity: 98/329 - (29%)
• Similarity: 158/329 - (48%)
• Gaps: 51/329 - (15%)

  Fly    50 LTTRMQSLNNEIASVKEQIGS-------LQEQLVDLRRAG----SAPVV---------------G 88
            :.||.:.|..:.||:.:.:.:       |:||.:.:....    |.|:|               |
Human   168 MATRYRELEVKYASLTDLVNNQSVMITLLEEQCLRIFSRQDTHVSPPLVQVVPQHIPNSQQYTPG 232

  Fly    89 LASPNALASRFPFSHNSLDIEPQLLANGGAAAVPITPANCLK-------QQ--------HGVVRI 138
            |...|.: .|.|.....|...|.|..:...:...|.|...:.       ||        .|:..|
Human   233 LLGGNEI-QRDPGYPRDLMPPPDLATSPTKSPFKIPPVTFINEGPFKDCQQAKEAGHSVSGIYMI 296

  Fly   139 RPRSNVEPFFVFCDQKVRNGGWTMVVNRYDGSEDFNRKWADYKIGFGPLTTEFFIGLDKLHQITS 203
            :|.::..|..::|:..:..||||::..|.|||.:|.|.|.:||.|||.:..|:::||:.::.:::
Human   297 KPENSNGPMQLWCENSLDPGGWTVIQKRTDGSVNFFRNWENYKKGFGNIDGEYWLGLENIYMLSN 361

  Fly   204 SDNYELLVQLQNRKQELRYALYDHFSIGSESEQYRLNVLGDYHGDAADALRDHTGKKFSTHDRVN 268
            .|||:||::|::...:..||.|..|.:..|||.|||. ||.|.|:|.|::..|.||:|:|.||..
Human   362 QDNYKLLIELEDWSDKKVYAEYSSFRLEPESEFYRLR-LGTYQGNAGDSMMWHNGKQFTTLDRDK 425

  Fly   269 DENEQNCAAQQSGAFWYGGSCNLTNPFGLYQR---LLERDVDGFKGILWRGFLNGPKGSLKIVRM 330
            |....|||....|.:|| .:|..:|..|::.|   ...:..|   ||.|..: .|...||:.|:|
Human   426 DMYAGNCAHFHKGGWWY-NACAHSNLNGVWYRGGHYRSKHQD---GIFWAEY-RGGSYSLRAVQM 485

  Fly   331 MVRP 334
            |::|
Human   486 MIKP 489

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	79/230 (34%)
ANGPTL1	NP_004664.1	PB1	74..138	CDD:413452
		FReD	275..490	CDD:238040	77/221 (35%)