Protein Alignment CG1889 and ANGPTL6

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: XP_011526650.1
• Gene: ANGPTL6 / 83854
• HGNCID: 23140
• Length: 537
• Species: Homo sapiens
• Alignment Length: 358
• Identity: 111/358 - (31%)
• Similarity: 157/358 - (43%)
• Gaps: 78/358 - (21%)

  Fly     6 QLDALVMAMACLSTTQTDL-----------GGG---LLVPPSLGNASSSSCPVSALSGLTTRMQS 56
            |||.....:|.|.|.|:.|           .||   :|.||.|    ....||..:...:...:.
Human   226 QLDVKFRELAQLVTQQSSLIARLERLCPGGAGGQQQVLPPPPL----VPVVPVRLVGSTSDTSRM 286

  Fly    57 LNNEIASVKEQIGSLQEQLVDLRRAGSAPVVGLASPNALASRFPFSHNSLDIEPQLLANGGAAAV 121
            |:......::|....||                    .:||..|..|               .||
Human   287 LDPAPEPQRDQTQRQQE--------------------PMASPMPAGH---------------PAV 316

  Fly   122 PITPA----NCLK------QQHGVVRIRPRSNVEPFFVFCDQKVRNGGWTMVVNRYDGSEDFNRK 176
            |..|.    :|.:      :|.||..:|...:|  ..|:|:|::..||||::..|.|||.:|...
Human   317 PTKPVGPWQDCAEARQAGHEQSGVYELRVGRHV--VSVWCEQQLEGGGWTVIQRRQDGSVNFFTT 379

  Fly   177 WADYKIGFGPLTTEFFIGLDKLHQITSSDNYELLVQLQNRKQELRYALYDHFSIGSESEQYRLNV 241
            |..||.|||....|:::||:.::|:||..::||||.|::.......|.||.||:..||:.|||.
Human   380 WQHYKAGFGRPDGEYWLGLEPVYQLTSRGDHELLVLLEDWGGRGARAHYDGFSLEPESDHYRLR- 443

  Fly   242 LGDYHGDAADALRDHTGKKFSTHDRVNDENEQNCAAQQSGAFWYGGSCNLTNPFGLYQ-----RL 301
            ||.|||||.|:|..|..|.|||.||..|....|||..|.|.:|| .:|..:|..|::.     |.
Human   444 LGQYHGDAGDSLSWHNDKPFSTVDRDRDSYSGNCALYQRGGWWY-HACAHSNLNGVWHHGGHYRS 507

  Fly   302 LERDVDGFKGILWRGFLNGPKGSLKIVRMMVRP 334
            ..:|     |:.|..|..|.. ||:...|::||
Human   508 RYQD-----GVYWAEFRGGAY-SLRKAAMLIRP 534

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	84/227 (37%)
ANGPTL6	XP_011526650.1	FReD	322..535	CDD:238040	83/223 (37%)