Protein Alignment CG1889 and Tnxb

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001415265.1
• Gene: Tnxb / 81877
• MGIID: 1932137
• Length: 4361
• Species: Mus musculus
• Alignment Length: 286
• Identity: 94/286 - (32%)
• Similarity: 139/286 - (48%)
• Gaps: 41/286 - (14%)

  Fly    69 GSLQEQLVDLRRAGSAPVVGLASPNALASRFPFSHNSLDIE--------PQLLAN--GGAAAVPI 123
            |.:||.|:.   ||:       :.:.|...||.:..|..:.        |.:|.:  .|...:|.
Mouse  4089 GQIQEILLP---AGT-------TSHRLLRLFPSTFYSAQLRAIWGESLTPPVLTSFTTGGLRIPF 4143

  Fly   124 TPANCLKQ-QHG-----VVRIRPRSNVE-PFFVFCDQKVRNGGWTMVVNRYDGSEDFNRKWADYK 181
             |.:|.:: ::|     ...|....|.| |..||||.:...|||.:...|.||..||.|.|.:|.
Mouse  4144 -PRDCGEELKNGPSASKTTTIFLNGNRERPLDVFCDMETDGGGWLVFQRRMDGQTDFWRDWEEYA 4207

  Fly   182 IGFGPLTTEFFIGLDKLHQITSSDNYELLVQLQNRKQELRYALYDHFSIGSESEQYRLNVLGDYH 246
            .|||.::.||::|.:.||.:|.:.:|.|.|.|:..|:.: :|.||.|.:.|..|.|||::.| ||
Mouse  4208 HGFGNISGEFWLGNEALHSLTQAGDYSLRVDLRAGKEAV-FAQYDFFRVDSAKENYRLHLEG-YH 4270

  Fly   247 GDAADALRDHTGKKFSTHDRVNDENEQ--NCAAQQSGAFWYGGSCNLTNPFGLYQRLLERDVDGF 309
            |.|.|::..|:|..||..||  |.|..  :||....||:|| .:|:..|..|||...:  |..|.
Mouse  4271 GTAGDSMSYHSGSVFSARDR--DPNNLLISCAVSYRGAWWY-RNCHYANLNGLYGSTV--DHQGV 4330

  Fly   310 KGILWRGFLNGPKGSLKIVRMMVRPR 335
            ....|:||    :.|:....|.:|||
Mouse  4331 SWYHWKGF----EFSVPFTEMKLRPR 4352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	78/220 (35%)
Tnxb	NP_001415265.1	EGF_2	177..200	CDD:400365
		EGF_2	208..231	CDD:400365
		EGF_Tenascin	236..262	CDD:480934
		EGF_Tenascin	267..293	CDD:480934
		EGF_Tenascin	298..325	CDD:480934
		C_rich_MXAN6577	301..432	CDD:469225
		EGF_Tenascin	422..448	CDD:480934
		EGF_2	456..479	CDD:400365
		EGF_Tenascin	484..510	CDD:480934
		EGF_Tenascin	515..542	CDD:480934
		EGF_Tenascin	546..572	CDD:480934
		C_rich_MXAN6577	581..690	CDD:469225
		EGF_Tenascin	706..732	CDD:480934
		fn3	737..818	CDD:394996
		fn3	830..906	CDD:394996
		FN3	1076..1138	CDD:473895
		fn3	1292..1369	CDD:394996
		FN3	1386..1466	CDD:238020
		fn3	1484..1557	CDD:394996
		fn3	1599..1676	CDD:394996
		fn3	1707..1777	CDD:394996
		fn3	1801..1881	CDD:394996
		fn3	1904..1971	CDD:394996
		fn3	2000..2067	CDD:394996
		fn3	2102..2164	CDD:394996
		FN3	2211..2279	CDD:238020
		fn3	2315..2395	CDD:394996
		fn3	2426..2496	CDD:394996
		fn3	2522..2602	CDD:394996
		fn3	2636..2709	CDD:394996
		fn3	2748..2825	CDD:394996
		fn3	2861..2931	CDD:394996
		fn3	2970..3045	CDD:394996
		fn3	3076..3146	CDD:394996
		fn3	3183..3260	CDD:394996
		FN3	3259..3691	CDD:442628
		fn3	3569..3644	CDD:394996
		fn3	3679..3752	CDD:394996
		fn3	3773..3855	CDD:394996
		FN3	<3842..>4086	CDD:442628
		FN3	3876..3955	CDD:238020
		fn3	4052..4129	CDD:394996	10/49 (20%)
		Fibrinogen_C	4143..4352	CDD:395095	78/220 (35%)