Protein Alignment CG1889 and TNXB

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001415264.1
• Gene: TNXB / 7148
• HGNCID: 11976
• Length: 4491
• Species: Homo sapiens
• Alignment Length: 263
• Identity: 88/263 - (33%)
• Similarity: 123/263 - (46%)
• Gaps: 41/263 - (15%)

  Fly   102 SHNSLDIEPQLLANG--------------------GAAAVPITPANCLKQ-QHGVVRIRP----- 140
            ||..|.:.|....|.                    |...:|. |.:|.:: |:|....|.
Human  4232 SHQLLGLFPSTSYNARLQAMWGQSLLPPVSTSFTTGGLRIPF-PRDCGEEMQNGAGASRTSTIFL 4295

  Fly   141 RSNVE-PFFVFCDQKVRNGGWTMVVNRYDGSEDFNRKWADYKIGFGPLTTEFFIGLDKLHQITSS 204
            ..|.| |..||||.:...|||.:...|.||..||.|.|.||..|||.::.||::|.:.||.:|.:
Human  4296 NGNRERPLNVFCDMETDGGGWLVFQRRMDGQTDFWRDWEDYAHGFGNISGEFWLGNEALHSLTQA 4360

  Fly   205 DNYELLVQLQNRKQELRYALYDHFSIGSESEQYRLNVLGDYHGDAADALRDHTGKKFSTHDRVND 269
            .:|.:.|.|: ...|..:|.||.|.:.|.:|.|||::.| |||.|.|::..|:|..||..||  |
Human  4361 GDYSMRVDLR-AGDEAVFAQYDSFHVDSAAEYYRLHLEG-YHGTAGDSMSYHSGSVFSARDR--D 4421

  Fly   270 ENEQ--NCAAQQSGAFWYGGSCNLTNPFGLYQRLLERDVDGFKGILWRGFLNGPKGSLKIVRMMV 332
            .|..  :||....||:|| .:|:..|..|||...:  |..|.....|:||    :.|:....|.:
Human  4422 PNSLLISCAVSYRGAWWY-RNCHYANLNGLYGSTV--DHQGVSWYHWKGF----EFSVPFTEMKL 4479

  Fly   333 RPR 335
            |||
Human  4480 RPR 4482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	79/220 (36%)
TNXB	NP_001415264.1	C_rich_MXAN6577	<191..295	CDD:469225
		EGF_Tenascin	249..275	CDD:480934
		PTZ00214	<254..669	CDD:173479
		EGF_Tenascin	311..337	CDD:480934
		C_rich_MXAN6577	314..418	CDD:469225
		EGF_Tenascin	373..399	CDD:480934
		EGF_Tenascin	559..585	CDD:480934
		EGF_Tenascin	719..745	CDD:480934
		fn3	762..831	CDD:394996
		fn3	843..919	CDD:394996
		fn3	1114..1161	CDD:394996
		fn3	1308..1388	CDD:394996
		FN3	1403..1485	CDD:238020
		fn3	1512..1589	CDD:394996
		fn3	1623..1693	CDD:394996
		FN3	<1673..2048	CDD:442628
		FN3	2020..2109	CDD:238020
		fn3	2132..2202	CDD:394996
		fn3	2235..2308	CDD:394996
		fn3	2346..2416	CDD:394996
		fn3	2445..2515	CDD:394996
		fn3	2551..2624	CDD:394996
		FN3	<2665..>2895	CDD:442628
		fn3	2773..2843	CDD:394996
		fn3	2876..2956	CDD:394996
		fn3	2990..3057	CDD:394996
		fn3	3092..3172	CDD:394996
		fn3	3206..3273	CDD:394996
		fn3	3308..3381	CDD:394996
		FN3	3384..>3762	CDD:442628
		fn3	3809..3884	CDD:394996
		fn3	3903..3985	CDD:394996
		fn3	4005..4083	CDD:394996
		FN3	<4061..>4251	CDD:442628	5/18 (28%)
		fn3	4182..4259	CDD:394996	5/26 (19%)
		Fibrinogen_C	4273..4482	CDD:395095	79/220 (36%)