Protein Alignment CG1889 and ANGPT2

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001138.1
• Gene: ANGPT2 / 285
• HGNCID: 485
• Length: 496
• Species: Homo sapiens
• Alignment Length: 303
• Identity: 89/303 - (29%)
• Similarity: 147/303 - (48%)
• Gaps: 40/303 - (13%)

  Fly    47 LSGLTTRMQSLNNEI------ASVKEQIGSLQEQLVDLRRAGSAPVVGLASPNALASRFPFSHNS 105
            |..|.::..|:..|:      |:|...:  ||:|..||          :.:.|.|.:....|:::
Human   216 LQVLVSKQNSIIEELEKKIVTATVNNSV--LQKQQHDL----------METVNNLLTMMSTSNSA 268

  Fly   106 LDIEPQLLANGGAAAVPITPANC---LKQQH---GVVRIRPRSNVEPFFVFCDQKVRNGGWTMVV 164
            .|  |.:     |....|:..:|   .|..|   |:..:...::.|....:||.:...||||::.
Human   269 KD--PTV-----AKEEQISFRDCAEVFKSGHTTNGIYTLTFPNSTEEIKAYCDMEAGGGGWTIIQ 326

  Fly   165 NRYDGSEDFNRKWADYKIGFGPLTTEFFIGLDKLHQITSSDNYELLVQLQNRKQELRYALYDHFS 229
            .|.|||.||.|.|.:||:|||..:.|:::|.:.:.|:|:...|.|.:.|::.:....|:||:||.
Human   327 RREDGSVDFQRTWKEYKVGFGNPSGEYWLGNEFVSQLTNQQRYVLKIHLKDWEGNEAYSLYEHFY 391

  Fly   230 IGSESEQYRLNVLGDYHGDAAD-ALRDHTGKKFSTHDRVNDENEQNCAAQQSGAFWYGGSCNLTN 293
            :.||...||:::.| ..|.|.. :.....|..|||.|..||:....|:...:|.:|: .:|..:|
Human   392 LSSEELNYRIHLKG-LTGTAGKISSISQPGNDFSTKDGDNDKCICKCSQMLTGGWWF-DACGPSN 454

  Fly   294 PFGLY--QRLLERDVDGFKGILWRGFLNGPKGSLKIVRMMVRP 334
            ..|:|  ||   ::.:.|.||.|. :..|...|||...||:||
Human   455 LNGMYYPQR---QNTNKFNGIKWY-YWKGSGYSLKATTMMIRP 493

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	72/221 (33%)
ANGPT2	NP_001138.1	CCDC158	<78..>295	CDD:464943	21/97 (22%)
		FBG	280..494	CDD:214548	71/220 (32%)