Protein Alignment CG1889 and ANGPT1

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_001137.2
• Gene: ANGPT1 / 284
• HGNCID: 484
• Length: 498
• Species: Homo sapiens
• Alignment Length: 302
• Identity: 90/302 - (29%)
• Similarity: 139/302 - (46%)
• Gaps: 39/302 - (12%)

  Fly    47 LSGLTTR----MQSLNNEIASVKEQIGSLQEQLVDLRRAGSAPVVGLASPNALASRFPFSHNSLD 107
            |.||.||    :|.|..::.........||:|.::|                    ....||.::
Human   219 LQGLVTRQTYIIQELEKQLNRATTNNSVLQKQQLEL--------------------MDTVHNLVN 263

  Fly   108 I--EPQLLANGGAAAVPITPANCLK------QQHGVVRIRPRSNVEPFFVFCDQKVRNGGWTMVV 164
            :  :..:|..||.........:|..      .:.|:..|...:..||..|||:..|..||||::.
Human   264 LCTKEGVLLKGGKREEEKPFRDCADVYQAGFNKSGIYTIYINNMPEPKKVFCNMDVNGGGWTVIQ 328

  Fly   165 NRYDGSEDFNRKWADYKIGFGPLTTEFFIGLDKLHQITSSDNYELLVQLQNRKQELRYALYDHFS 229
            :|.|||.||.|.|.:||:|||..:.|:::|.:.:..|||...|.|.::|.:.:....|:.||.|.
Human   329 HREDGSLDFQRGWKEYKMGFGNPSGEYWLGNEFIFAITSQRQYMLRIELMDWEGNRAYSQYDRFH 393

  Fly   230 IGSESEQYRLNVLGDYHGDAA--DALRDHTGKKFSTHDRVNDENEQNCAAQQSGAFWYGGSCNLT 292
            ||:|.:.|||.:.| :.|.|.  .:|..| |..|||.|..||.....||...:|.:|: .:|..:
Human   394 IGNEKQNYRLYLKG-HTGTAGKQSSLILH-GADFSTKDADNDNCMCKCALMLTGGWWF-DACGPS 455

  Fly   293 NPFGLYQRLLERDVDGFKGILWRGFLNGPKGSLKIVRMMVRP 334
            |..|::. ...::.....||.|. :..||..||:...||:||
Human   456 NLNGMFY-TAGQNHGKLNGIKWH-YFKGPSYSLRSTTMMIRP 495

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	74/220 (34%)
ANGPT1	NP_001137.2	Mplasa_alph_rch	<105..>258	CDD:275316	11/58 (19%)
		FReD	281..496	CDD:238040	74/220 (34%)