Protein Alignment CG1889 and ANGPTL3

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_055310.1
• Gene: ANGPTL3 / 27329
• HGNCID: 491
• Length: 460
• Species: Homo sapiens
• Alignment Length: 293
• Identity: 80/293 - (27%)
• Similarity: 137/293 - (46%)
• Gaps: 30/293 - (10%)

  Fly    54 MQSLNNEIASVKEQIGSLQEQLVDLRRAG-SAPV-VGLASPNALASRFPF---------SHNSLD 107
            :|::.::...:.:|...::|....|||.. ..|. :.|:|........||         .|:.:.
Human   179 LQTVEDQYKQLNQQHSQIKEIENQLRRTSIQEPTEISLSSKPRAPRTTPFLQLNEIRNVKHDGIP 243

  Fly   108 IEPQLLANGGAAAVPITPANCLKQQHGVVRIRPRSNVEPFFVFCDQKVRNGGWTMVVNRYDGSED 172
            .|...:.|.|            :...|:..||| ||.:.|.|:|| .:....||::.:|.|||::
Human   244 AECTTIYNRG------------EHTSGMYAIRP-SNSQVFHVYCD-VISGSPWTLIQHRIDGSQN 294

  Fly   173 FNRKWADYKIGFGPLTTEFFIGLDKLHQITSSDNYELLVQLQNRKQELRYALYDHFSIGSESEQY 237
            ||..|.:||.|||.|..||::||:|::.|....||.|.::|::.|....|..|. |.:|:....|
Human   295 FNETWENYKYGFGRLDGEFWLGLEKIYSIVKQSNYVLRIELEDWKDNKHYIEYS-FYLGNHETNY 358

  Fly   238 RLNVLGDYHGDAADALRDHTGKKFSTHDRVNDENEQNCAAQQSGAFWYGGSCNLTNPFGLYQR-L 301
            .|:::. ..|:..:|:.::....|||.|. ..:...||....||.:|:...|...|..|.|.: .
Human   359 TLHLVA-ITGNVPNAIPENKDLVFSTWDH-KAKGHFNCPEGYSGGWWWHDECGENNLNGKYNKPR 421

  Fly   302 LERDVDGFKGILWRGFLNGPKGSLKIVRMMVRP 334
            .:...:..:|:.|:. .||...|:|..:|::.|
Human   422 AKSKPERRRGLSWKS-QNGRLYSIKSTKMLIHP 453

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	65/213 (31%)
ANGPTL3	NP_055310.1	GumC	<81..>205	CDD:442439	4/25 (16%)
		FReD	243..453	CDD:238040	67/227 (30%)