Protein Alignment CG1889 and ANGPTL2

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_036230.1
• Gene: ANGPTL2 / 23452
• HGNCID: 490
• Length: 493
• Species: Homo sapiens
• Alignment Length: 320
• Identity: 99/320 - (30%)
• Similarity: 150/320 - (46%)
• Gaps: 36/320 - (11%)

  Fly    45 SALSGLTTRMQSLNNEIASVKEQIGSLQEQLVDLRRAGSAPVVGLASP-------------NALA 96
            |....|..:.|.|.....:..|.|..|:|....:..|...|....|:|             |.::
Human   174 SKYKDLEHKYQHLATLAHNQSEIIAQLEEHCQRVPSARPVPQPPPAAPPRVYQPPTYNRIINQIS 238

  Fly    97 SRFPFSHNSLDI-------EPQLLANGGAAAVPITP-ANCLK------QQHGVVRIRPRSNVEPF 147
            :....|..:|.:       .|.|.:...:...|..| .:||:      ....:..::|.:.....
Human   239 TNEIQSDQNLKVLPPPLPTMPTLTSLPSSTDKPSGPWRDCLQALEDGHDTSSIYLVKPENTNRLM 303

  Fly   148 FVFCDQKVRNGGWTMVVNRYDGSEDFNRKWADYKIGFGPLTTEFFIGLDKLHQITSSDNYELLVQ 212
            .|:|||:...||||::..|.|||.:|.|.|..||.|||.:..|:::||:.::.:|:..||:|||.
Human   304 QVWCDQRHDPGGWTVIQRRLDGSVNFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVT 368

  Fly   213 LQNRKQELRYALYDHFSIGSESEQYRLNVLGDYHGDAADALRDHTGKKFSTHDRVNDENEQNCAA 277
            :::......:|.|..|.:..|||.|:|. ||.|||:|.|:...|.||:|:|.||.:|....|||.
Human   369 MEDWSGRKVFAEYASFRLEPESEYYKLR-LGRYHGNAGDSFTWHNGKQFTTLDRDHDVYTGNCAH 432

  Fly   278 QQSGAFWYGGSCNLTNPFGLYQR---LLERDVDGFKGILWRGFLNGPKGSLKIVRMMVRP 334
            .|.|.:|| .:|..:|..|::.|   ...|..|   |:.|..| .|...|||.|.||:||
Human   433 YQKGGWWY-NACAHSNLNGVWYRGGHYRSRYQD---GVYWAEF-RGGSYSLKKVVMMIRP 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	81/222 (36%)
ANGPTL2	NP_036230.1	FReD	273..487	CDD:238040	79/219 (36%)