Protein Alignment CG1889 and FGG

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_068656.2
• Gene: FGG / 2266
• HGNCID: 3694
• Length: 453
• Species: Homo sapiens
• Alignment Length: 313
• Identity: 90/313 - (28%)
• Similarity: 140/313 - (44%)
• Gaps: 59/313 - (18%)

  Fly    45 SALSGLTTRMQSLNNEIASVKEQIGSLQEQLVDLRRAGSAPVVGLASPNALASRFPFSHNSLDIE 109
            |::..|.....|.|.:|.::||::..|:.|..:       |......          .|:....:
Human   131 SSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE-------PCKDTVQ----------IHDITGKD 178

  Fly   110 PQLLANGGAAAVPITPANCLKQQHGVVRIRPRSNVEPFFVFCDQKVRNGGWTMVVNRYDGSEDFN 174
            .|.:||.||            :|.|:..|:|....:.|.|:|:......|||:...|.|||.||.
Human   179 CQDIANKGA------------KQSGLYFIKPLKANQQFLVYCEIDGSGNGWTVFQKRLDGSVDFK 231

  Fly   175 RKWADYKIGFGPL----TTEFFIGLDKLHQIT--SSDNYELLVQLQNRKQELRYALYDHFSIGSE 233
            :.|..||.|||.|    ||||::|.:|:|.|:  |:..|.|.|:|::.......|.|..|.:|.|
Human   232 KNWIQYKEGFGHLSPTGTTEFWLGNEKIHLISTQSAIPYALRVELEDWNGRTSTADYAMFKVGPE 296

  Fly   234 SEQYRLNVLGDYHGDAADA--------------LRDHTGKKFSTHDRVNDENEQNCAAQQSGAFW 284
            :::|||.......|||.||              ...|.|.:|||.|..||:.|.|| |:|.|:.|
Human   297 ADKYRLTYAYFAGGDAGDAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNC-AEQDGSGW 360

  Fly   285 YGGSCNLTNPFGLYQR----LLERDVDGF-KGILW----RGFLNGPKGSLKIV 328
            :...|:..:..|:|.:    ......:|: .||:|    ..:.:..|.::||:
Human   361 WMNKCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKII 413

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	74/235 (31%)
FGG	NP_068656.2	Fib_alpha	30..172	CDD:462570	10/57 (18%)
		Fibrinogen_C	175..414	CDD:395095	79/252 (31%)
		Gamma-chain polymerization, binding amino end of another fibrin alpha chain	400..422		3/14 (21%)
		Platelet aggregation and Staphylococcus clumping	423..437
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	424..453