Protein Alignment CG1889 and FCN2

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_004099.2
• Gene: FCN2 / 2220
• HGNCID: 3624
• Length: 313
• Species: Homo sapiens
• Alignment Length: 349
• Identity: 108/349 - (30%)
• Similarity: 140/349 - (40%)
• Gaps: 84/349 - (24%)

  Fly    24 LGGGLLVPPSLGNA----SSSSCPVSALSGLTTRMQSLNNEIASVKEQIGSLQEQLVDLRRAGSA 84
            ||...|:...||.|    ::.:||...:.||.                 ||  ::|..||.....
Human    10 LGAATLLLSFLGMAWALQAADTCPEVKMVGLE-----------------GS--DKLTILRGCPGL 55

  Fly    85 PVVGLASPNALA----------------SRFPFSHNSLDIEPQLLANGGAAAVPITPANC----- 128
            |  |...|...|                ...|...|....|||....|        |..|
Human    56 P--GAPGPKGEAGTNGKRGERGPPGPPGKAGPPGPNGAPGEPQPCLTG--------PRTCKDLLD 110

  Fly   129 ----LKQQHGVVRIRPRSNVEPFFVFCDQKVRNGGWTMVVNRYDGSEDFNRKWADYKIGFGPLTT 189
                |...|.:.    ..:..|..|.||.....||||:...|.|||.||.|.||.||.|||....
Human   111 RGHFLSGWHTIY----LPDCRPLTVLCDMDTDGGGWTVFQRRVDGSVDFYRDWATYKQGFGSRLG 171

  Fly   190 EFFIGLDKLHQITSSDNYELLVQLQNRKQELRYALYDHFSIGSESEQYRLNVLGDY-HGDAADAL 253
            ||::|.|.:|.:|:....||.|.|.:.:...::|.|..|.:..|:|:|.| |||.: .|.|.|:|
Human   172 EFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSFKVADEAEKYNL-VLGAFVEGSAGDSL 235

  Fly   254 RDHTGKKFSTHDRVNDENEQNCAAQQSGAFWYGGSCNLTNPFGLYQRLLERDVDGFKGILWRGFL 318
            ..|..:.|||.|:.||.|..|||....||:|| .:|:::|..|.|.|       |..|    .|.
Human   236 TFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWY-KNCHVSNLNGRYLR-------GTHG----SFA 288

  Fly   319 NG-----PKG---SLKIVRMMVRP 334
            ||     .||   |.|:..|.|||
Human   289 NGINWKSGKGYNYSYKVSEMKVRP 312

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	83/230 (36%)
FCN2	NP_004099.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	51..99		9/49 (18%)
		FReD	102..312	CDD:238040	81/226 (36%)