Protein Alignment CG1889 and FGL2

DIOPT Version :10

• Sequence 1: NP_727376.2
• Gene: CG1889 / 31928
• FlyBaseID: FBgn0030164
• Length: 338
• Species: Drosophila melanogaster
• Sequence 2: NP_006673.1
• Gene: FGL2 / 10875
• HGNCID: 3696
• Length: 439
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 108/355 - (30%)
• Similarity: 156/355 - (43%)
• Gaps: 61/355 - (17%)

  Fly    21 QTDLGG-----GLLVPPSLGNASSSSCP----VSALSGLTTRMQSLNNEIASVKEQIGSLQEQLV 76
            |.|..|     |||:|       |:..|    .:.:..|.:.:..|::|:.:.||:|..|..:|.
Human   102 QADDNGDPGRNGLLLP-------STGAPGEVGDNRVRELESEVNKLSSELKNAKEEINVLHGRLE 159

  Fly    77 DLRRAGSAPVVGLASPNALASRFPFSHNSLDIEPQLLANGGAAAVP------------ITPANCL 129
            .|.......:....  ::..:...|..||||        |..:..|            :...:|.
Human   160 KLNLVNMNNIENYV--DSKVANLTFVVNSLD--------GKCSKCPSQEQIQSRPVQHLIYKDCS 214

  Fly   130 ------KQQHGVVRIRPRSNVEPFFVFCDQKVRNGGWTMVVNRYDGSEDFNRKWADYKIGFGPLT 188
                  |:.....|:.|......|.|:||.:...||||::..|.|||.:|.|.|.|||.|||.|.
Human   215 DYYAIGKRSSETYRVTPDPKNSSFEVYCDMETMGGGWTVLQARLDGSTNFTRTWQDYKAGFGNLR 279

  Fly   189 TEFFIGLDKLHQITSSDNYELLVQLQNRKQELRYALYDHFSIGSESEQYRLNVLGDYHGDAADAL 253
            .||::|.||:|.:|.|....|.:.|::......|||||.|.:.:|..:|||:| |:|:|.|.|||
Human   280 REFWLGNDKIHLLTKSKEMILRIDLEDFNGVELYALYDQFYVANEFLKYRLHV-GNYNGTAGDAL 343

  Fly   254 R-----DHTGKKFSTHDRVNDENEQ-NCAAQQSGAFWYGGSCNLTNPFGLYQRLLERDVDGFKGI 312
            |     :|..|.|:|.|:.||.... ||....|..:|: .:|...|..|.|.....|.|.  .||
Human   344 RFNKHYNHDLKFFTTPDKDNDRYPSGNCGLYYSSGWWF-DACLSANLNGKYYHQKYRGVR--NGI 405

  Fly   313 LW-------RGFLNGPKGSLKIVRMMVRPR 335
            .|       .....|.|.|.|..:||:||:
Human   406 FWGTWPGVSEAHPGGYKSSFKEAKMMIRPK 435

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1889	NP_727376.2	FReD	123..335	CDD:238040	82/230 (36%)
FGL2	NP_006673.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	103..126		8/29 (28%)
		Fibrinogen_C	209..435	CDD:395095	82/229 (36%)