DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1791 and angptl2a

DIOPT Version :9

Sequence 1:	NP_572591.1	Gene:	CG1791 / 31927	FlyBaseID:	FBgn0030163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001025401.1	Gene:	angptl2a / 569092	ZFINID:	ZDB-GENE-080721-15	Length:	525	Species:	Danio rerio

Alignment Length:	293	Identity:	97/293 - (33%)
Similarity:	139/293 - (47%)	Gaps:	70/293 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 MTDELQN----------LKTELNE----------------LQGLIEEYKNQGTGIPIATRLLRPL 102
            ||:|:|:          |.||.:|                ||.|.|.:.|.|      ..||:
Zfish   271 MTNEIQSDQNSKAMPSALPTEQSETHSFSTDKLSGPFKDCLQALEEGHSNSG------MFLLK-- 327

  Fly   103 PASVQTFPLALATPPDDTPRNCYDEKHGQVRIRIAPDMEPFFASCDQKVRDGGWMVIAYRFDGSE 167
                          |::|      .|..||             .|||:...|||.||..|.|||.
Zfish   328 --------------PENT------NKLMQV-------------WCDQRHDPGGWTVIQRRMDGSV 359

  Fly   168 DFNKDWQNYKAGFGALNSEFFIGLDKLHRLTNSEHHELLIIMKKKSGEERFALYDHFSIGSESEK 232
            :|.::|:.||.|||.::.|:::||:.::.|||..:::||:.::..||.:.||.|..|.:..|::.
Zfish   360 NFFRNWETYKQGFGNIDGEYWLGLENIYWLTNQGNYKLLVTLEDWSGRKTFAEYASFRLEPEADF 424

  Fly   233 YLLYVLGAYKGDAGDSLRYHAGKKFTTFDQDNDDNGQNCARTHAGAWWYGRECFESNLFGTFQSK 297
            |.:.| |.|.|:||||:.:|.||:|||.|:|:|....|||....|.||| ..|..|||.|.:...
Zfish   425 YKMRV-GRYHGNAGDSMTWHNGKQFTTLDRDHDAYTGNCAHYQKGGWWY-NACAHSNLNGVWYRG 487

  Fly   298 YGQEIGYFKGILWKSFLPGPTGSLSYVRMLIRP 330
            ......|..|:.|..| .|.:.||..|.|:|||
Zfish   488 GHYRSRYQDGVYWAEF-RGGSYSLKKVTMMIRP 519

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1791	NP_572591.1	FReD	119..331	CDD:238040	80/212 (38%)
angptl2a	NP_001025401.1	DUF1875	<50..>147	CDD:286100
		Fib_alpha	119..215	CDD:285864
		FReD	305..519	CDD:238040	87/257 (34%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	145	1.000	Inparanoid score	I4411
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.860