DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1791 and angptl6

DIOPT Version :9

Sequence 1:	NP_572591.1	Gene:	CG1791 / 31927	FlyBaseID:	FBgn0030163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001014821.1	Gene:	angptl6 / 561927	ZFINID:	ZDB-GENE-030131-9735	Length:	489	Species:	Danio rerio

Alignment Length:	326	Identity:	105/326 - (32%)
Similarity:	145/326 - (44%)	Gaps:	64/326 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    53 TLAGLA---ARVQFMTDELQNLKTELNELQGLIEEYKNQGTGIP---------IATRLLRPLPAS 105
            |||.|.   :::..:.::...|||...|||        :.|.:|         |.|.     |..
Zfish   179 TLASLVNNQSKIITLLEKQCQLKTSTKELQ--------EATSLPAQQSSVLVNINTE-----PKD 230

  Fly   106 VQ-----TFPLALAT------------PPDDTP-------------RNCY------DEKHGQVRI 134
            ||     .|..|.|.            ||.:||             .:|:      ::..|...:
Zfish   231 VQRDQSAPFHQAQARQELLETFDDSPGPPTETPFISFPSTKSPGPWHDCHNVLESGEKTSGIYLL 295

  Fly   135 RIAPDMEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYKAGFGALNSEFFIGLDKLHRLTN 199
            |.........|.|||....|||.||..|.|||.:|.:.|..||.|||.|:.|:::||:.|:.||:
Zfish   296 RPRNTNRLLQAWCDQSRAQGGWTVIQRRQDGSVNFFRTWDQYKQGFGNLDGEYWLGLEHLYWLTS 360

  Fly   200 SEHHELLIIMKKKSGEERFALYDHFSIGSESEKYLLYVLGAYKGDAGDSLRYHAGKKFTTFDQDN 264
            ...::|.:.|:...|.:.:|.||.|.:..||:.|.|. ||:|:|.|||||.:|..|.|||.|:|.
Zfish   361 QATYKLRVAMEDWQGRQVYAEYDSFRVEPESDWYRLR-LGSYQGTAGDSLSWHNNKAFTTLDRDK 424

  Fly   265 DDNGQNCARTHAGAWWYGRECFESNLFGTFQSKYGQEIGYFKGILWKSFLPGPTGSLSYVRMLIR 329
            |....|||....|.||| ..|..|||.|.:.........|..|:.|..| .|.:.||..|.|:|:
Zfish   425 DAYTGNCAHYQKGGWWY-HMCAHSNLNGVWYRGGHYRSRYQDGVYWAEF-HGGSYSLKKVAMMIK 487

  Fly   330 P 330
            |
Zfish   488 P 488

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1791	NP_572591.1	FReD	119..331	CDD:238040	83/231 (36%)
angptl6	NP_001014821.1	DUF1640	<46..150	CDD:285090
		DUF4349	<126..230	CDD:305044	15/63 (24%)
		FReD	274..488	CDD:238040	80/216 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000029
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.810