DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1791 and angptl2b

DIOPT Version :9

Sequence 1:	NP_572591.1	Gene:	CG1791 / 31927	FlyBaseID:	FBgn0030163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001119950.1	Gene:	angptl2b / 503514	ZFINID:	ZDB-GENE-050624-1	Length:	519	Species:	Danio rerio

Alignment Length:	269	Identity:	93/269 - (34%)
Similarity:	137/269 - (50%)	Gaps:	35/269 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    76 NELQGLIEEYKNQGTGIPIATRLLRPLPASVQTFPLALATP-----PDDTPRNC---YDEKHGQV 132
            ||:|      .:|...:|         ||...|.|....:|     |....::|   .::.|...
Zfish   266 NEIQ------SDQNLKVP---------PAPPPTMPGGTHSPSTTNKPSGPWKDCLEALEDGHTNS 315

  Fly   133 RIR-IAPD-----MEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYKAGFGALNSEFFIGL 191
            .:. :.||     |:.:   |||:...|||.||..|.|||.:|.::|:.||.|||.::.|:::||
Zfish   316 GMHLVKPDNTNKLMQVW---CDQRQDPGGWTVIQRRMDGSVNFFRNWETYKQGFGNIDGEYWLGL 377

  Fly   192 DKLHRLTNSEHHELLIIMKKKSGEERFALYDHFSIGSESEKYLLYVLGAYKGDAGDSLRYHAGKK 256
            :.::.:||..:::||:.::..||.:.||.|..|.:..|::.|.|.| |.|.|:|||||.:|.||:
Zfish   378 ENIYWITNQGNYKLLVTLEDWSGRKTFAEYASFRLEPEADFYRLRV-GRYHGNAGDSLTWHNGKQ 441

  Fly   257 FTTFDQDNDDNGQNCARTHAGAWWYGRECFESNLFGTFQSKYGQEIGYFKGILWKSFLPGPTGSL 321
            |||.|:|:|....|||....|.||| ..|..|||.|.:.........|..|:.|..| .|...||
Zfish   442 FTTLDRDHDVYTGNCAHYQKGGWWY-NACAHSNLNGVWYRGGHYRSRYQDGVYWAEF-RGGAYSL 504

  Fly   322 SYVRMLIRP 330
            ..|.|:|||
Zfish   505 KKVVMMIRP 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1791	NP_572591.1	FReD	119..331	CDD:238040	82/221 (37%)
angptl2b	NP_001119950.1	RILP-like	98..216	CDD:304877
angptl2b	NP_001119950.1	FReD	299..513	CDD:238040	80/219 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	145	1.000	Inparanoid score	I4411
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.860