DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1791 and Angptl6

DIOPT Version :9

Sequence 1:	NP_572591.1	Gene:	CG1791 / 31927	FlyBaseID:	FBgn0030163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_001100172.1	Gene:	Angptl6 / 298698	RGDID:	1311141	Length:	457	Species:	Rattus norvegicus

Alignment Length:	422	Identity:	121/422 - (28%)
Similarity:	173/422 - (40%)	Gaps:	103/422 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LVTALACLSTTTNATSNLP------GKH---FSVIMRNSAEPFLL-------------------- 41
            :.|:..|.|:..:..|.|.      |:|   ...:.|.:||...|
  Rat    37 MATSAVCRSSEASQDSELATLRMRLGRHEELLRALQRRAAEGGALAGEVRALREHSLTLNTRLGQ 101

  Fly    42 ----------AENDTASCPVSTLA-------GLAARVQFMTDELQNLKTELNELQGLIEEY---- 85
                      ||.|..:.|.:.|.       |..|..:..|..||.|:.:|.|...|:.::
  Rat   102 LRAQLQQEAGAEPDLGAEPAAALGLLAERALGAEAEARRTTARLQQLEEQLREHAQLMSQHSSLL 166

  Fly    86 -----------KNQGTGIPIATRLLRPL------------------------------PAS-VQT 108
                       :.|...:|:....|.||                              |:| :.|
  Rat   167 GRLQRACASPERGQQQVLPLPLVPLVPLSLVGSASNTSRRLDQIPEHQREQSLRQQGPPSSPLPT 231

  Fly   109 FPLALATPPDDTPRNCYDE------KHGQVRIRIAPDMEPFFASCDQKVRDGGWMVIAYRFDGSE 167
            ..:|:.|.|....|:|.:.      :.|...:|:...:.|.:  |:|:...|||.||..|.|||.
  Rat   232 GHVAVPTRPVGPWRDCAEAQGAGHWQSGVYELRLGRRVVPVW--CEQQQEGGGWTVIQRRQDGSV 294

  Fly   168 DFNKDWQNYKAGFGALNSEFFIGLDKLHRLTNSEHHELLIIMKKKSGEERFALYDHFSIGSESEK 232
            :|..:||:||.|||..:.|:::||:.:|::|:...|||||::|...|....|.||.||:..||:.
  Rat   295 NFFTNWQHYKVGFGRPDGEYWLGLEPVHQVTSRGDHELLILLKDWGGRGARAHYDSFSLEPESDH 359

  Fly   233 YLLYVLGAYKGDAGDSLRYHAGKKFTTFDQDNDDNGQNCARTHAGAWWYGRECFESNLFGTFQSK 297
            |.|. ||.|.|||||||.:|:.|.|.|.|:|.|....|||..|.|.||| ..|..|||.|.:...
  Rat   360 YRLR-LGQYHGDAGDSLSWHSDKPFNTVDRDRDSYSGNCALYHRGGWWY-HACAHSNLNGVWYHG 422

  Fly   298 YGQEIGYFKGILWKSFLPGPTGSLSYVRMLIR 329
            ......|..|:.|..| .|...||....||.|
  Rat   423 GHYRSRYQDGVYWAEF-RGGAYSLKKAAMLTR 453

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1791	NP_572591.1	FReD	119..331	CDD:238040	85/217 (39%)
Angptl6	NP_001100172.1	Uso1_p115_C	66..>157	CDD:282695	17/90 (19%)
Angptl6	NP_001100172.1	FReD	242..453	CDD:238040	84/215 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.810