DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1791 and FGA

DIOPT Version :9

Sequence 1:	NP_572591.1	Gene:	CG1791 / 31927	FlyBaseID:	FBgn0030163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_000499.1	Gene:	FGA / 2243	HGNCID:	3661	Length:	866	Species:	Homo sapiens

Alignment Length:	247	Identity:	94/247 - (38%)
Similarity:	126/247 - (51%)	Gaps:	41/247 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly   113 LATPPDDTPRNCYDEKHGQVRIRIAPDMEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYK 177
            |.|.|..|       :.|...|::....:.|...|||:...|||::|..|.|||.:||:.||:||
Human   636 LQTHPSGT-------QSGIFNIKLPGSSKIFSVYCDQETSLGGWLLIQQRMDGSLNFNRTWQDYK 693

  Fly   178 AGFGALN----SEFFIGLDKLHRLTNSEHHELLIIMKKKSGEERFALYDHFSIGSESEKYLLYVL 238
            .|||:||    .||::|.|.||.|| .....|.:.::..:|.|.:|.| ||.:|||:|.|.|.|
Human   694 RGFGSLNDEGEGEFWLGNDYLHLLT-QRGSVLRVELEDWAGNEAYAEY-HFRVGSEAEGYALQV- 755

  Fly   239 GAYKGDAGDSL---------RY--HAGKKFTTFDQDNDDNGQNCARTHAGAWWYGRECFESNLFG 292
            .:|:|.|||:|         .|  |...:|:|||:|.|...:|||..:.|.||| ..|..:||.|
Human   756 SSYEGTAGDALIEGSVEEGAEYTSHNNMQFSTFDRDADQWEENCAEVYGGGWWY-NNCQAANLNG 819

  Fly   293 TF----------QSKYGQEIGYFKGILWKSFLPGPTGSLSYVRMLIRPLKKQ 334
            .:          .|.|..|    .|::|.|| .|...||..|||.||||..|
Human   820 IYYPGGSYDPRNNSPYEIE----NGVVWVSF-RGADYSLRAVRMKIRPLVTQ 866

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1791	NP_572591.1	FReD	119..331	CDD:238040	88/236 (37%)
FGA	NP_000499.1	Alpha-chain polymerization, binding distal domain of another fibrin gamma chain	36..38
		Fib_alpha	50..187	CDD:285864
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	262..460
		Fibrinogen_aC	445..509	CDD:288972
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	543..638		1/1 (100%)
		FReD	630..863	CDD:238040	91/242 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910