DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment CG1791 and FCN2

DIOPT Version :9

Sequence 1:NP_572591.1 Gene:CG1791 / 31927 FlyBaseID:FBgn0030163 Length:334 Species:Drosophila melanogaster
Sequence 2:NP_004099.2 Gene:FCN2 / 2220 HGNCID:3624 Length:313 Species:Homo sapiens


Alignment Length:304 Identity:109/304 - (35%)
Similarity:135/304 - (44%) Gaps:43/304 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly    48 SCPVSTLAGLAARVQFMTDELQNLKTELNELQGLIEEYKNQGTGIPIATRLLRPLPASVQTFPLA 112
            :||...:.||..     :|:|    |.|....||......:|.......|..|..|.     |..
Human    31 TCPEVKMVGLEG-----SDKL----TILRGCPGLPGAPGPKGEAGTNGKRGERGPPG-----PPG 81

  Fly   113 LATPPDDT------------PRNC---YDEKH---GQVRIRIAPDMEPFFASCDQKVRDGGWMVI 159
            .|.||...            ||.|   .|..|   |...|.: ||..|....||.....|||.|.
Human    82 KAGPPGPNGAPGEPQPCLTGPRTCKDLLDRGHFLSGWHTIYL-PDCRPLTVLCDMDTDGGGWTVF 145

  Fly   160 AYRFDGSEDFNKDWQNYKAGFGALNSEFFIGLDKLHRLTNSEHHELLIIMKKKSGEERFALYDHF 224
            ..|.|||.||.:||..||.|||:...||::|.|.:|.||.....||.:.:.......:||.|..|
Human   146 QRRVDGSVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRVDLVDFEDNYQFAKYRSF 210

  Fly   225 SIGSESEKYLLYVLGAY-KGDAGDSLRYHAGKKFTTFDQDNDDNGQNCARTHAGAWWYGRECFES 288
            .:..|:|||.| ||||: :|.|||||.:|..:.|:|.|||||.|..|||....||||| :.|..|
Human   211 KVADEAEKYNL-VLGAFVEGSAGDSLTFHNNQSFSTKDQDNDLNTGNCAVMFQGAWWY-KNCHVS 273

  Fly   289 NLFGTFQSKYGQEIGYFKGILWKSFLPGPTGSLSY--VRMLIRP 330
            ||.|.:..  |....:..||.|||   |...:.||  ..|.:||
Human   274 NLNGRYLR--GTHGSFANGINWKS---GKGYNYSYKVSEMKVRP 312

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG1791NP_572591.1 FReD 119..331 CDD:238040 91/233 (39%)
FCN2NP_004099.2 Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 51..99 10/52 (19%)
FReD 102..312 CDD:238040 89/217 (41%)