DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1791 and Angpt4

DIOPT Version :9

Sequence 1:	NP_572591.1	Gene:	CG1791 / 31927	FlyBaseID:	FBgn0030163	Length:	334	Species:	Drosophila melanogaster
Sequence 2:	NP_033771.1	Gene:	Angpt4 / 11602	MGIID:	1336887	Length:	509	Species:	Mus musculus

Alignment Length:	278	Identity:	89/278 - (32%)
Similarity:	137/278 - (49%)	Gaps:	21/278 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    65 TDELQNLKTELNEL---QGLIEEYKNQGTGIPIATRLLRPLPASVQTFPLALATPPDDTP--RNC 124
            |..|.|||..|:.|   ...:::.:.|.|  ....||:| :.|..| .|::|.||   .|  ::|
Mouse   240 TGTLANLKHNLHALSSNSSSLQQQQQQLT--EFVQRLVR-IVAQDQ-HPVSLKTP---KPVFQDC 297

  Fly   125 YDEKH------GQVRIRIAPDMEPFFASCDQKVRDGGWMVIAYRFDGSEDFNKDWQNYKAGFGAL 183
            .:.|.      |...|......:|....||.:...|||.:|.:|.|||.:|.:.|:.||.|||.:
Mouse   298 AEIKRSGVNTSGVYTIYETNMTKPLKVFCDMETDGGGWTLIQHREDGSVNFQRTWEEYKEGFGNV 362

  Fly   184 NSEFFIGLDKLHRLTNSEHHELLIIMKKKSGEERFALYDHFSIGSESEKYLLYVLGAYKGDAGDS 248
            ..|.::|.:.:||||:...:.|.:.:....|.:....|::|.:|||.::|.|.|..:.......:
Mouse   363 AREHWLGNEAVHRLTSRTAYLLRVELHDWEGRQTSIQYENFQLGSERQRYSLSVNDSSSSAGRKN 427

  Fly   249 LRYHAGKKFTTFDQDNDDNGQNCARTHAGAWWYGRECFESNLFGTFQSKYGQEIGYFKGILWKSF 313
            .....|.||:|.|.|||:....||:..:|.||:. .|..|||.|.:.|.: |.:....||.|..|
Mouse   428 SLAPQGTKFSTKDMDNDNCMCKCAQMLSGGWWFD-ACGLSNLNGIYYSVH-QHLHKINGIRWHYF 490

  Fly   314 LPGPTGSLSYVRMLIRPL 331
             .||:.||...||::||:
Mouse   491 -RGPSYSLHGTRMMLRPM 507

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1791	NP_572591.1	FReD	119..331	CDD:238040	70/219 (32%)
Angpt4	NP_033771.1	BMFP	140..217	CDD:294701
		FReD	292..507	CDD:238040	70/217 (32%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	416..436		2/19 (11%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG2579
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X25
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.900