DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idgf4 and Chi3l1

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001296749.1	Gene:	Chi3l1 / 89824	RGDID:	620874	Length:	391	Species:	Rattus norvegicus

Alignment Length:	451	Identity:	127/451 - (28%)
Similarity:	194/451 - (43%)	Gaps:	95/451 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLV 74
            |.|...:..:.:..::.|:|||...|..|||........|:.:|  |||::|.:|.|  |:|||
  Rat    15 LTGFAVLMLLQSCSAYKLVCYYTNWSQYREGNGSCFPDALDHSL--CTHIIYSFANI--SNNKL- 74

  Fly    75 SNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPFINSA 139
            |.:|..|:    :|:..:..||.:.|.||.||||||    ....:.::..::.::.:|..|:.|.
  Rat    75 STSEWNDV----TLYGMLNTLKTRNPRLKTLLSVGG----WSFGSERFSRIVSNAKSRKTFVQSV 131

  Fly   140 HSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVREL 204
            ...::|||||||||.|.:|..|.|                            :|   ||.|::||
  Rat   132 APFLRTYGFDGLDLAWLYPGPKDK----------------------------QH---FTTLIKEL 165

  Fly   205 KNAFRPDGYILGLSVLPNVNSSLF--------------FDVPAIINNLDYVNLHTYDFQTPERNN 255
            |..|..:       |.|.....|.              :||..|..:||::||.||||....|:
  Rat   166 KAEFTKE-------VQPGTEKLLLSAAVSAGKVTLDSGYDVAQIAQHLDFINLMTYDFHGTWRH- 222

  Fly   256 EVADFPAPIYE-LNERNPE--FNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPP 317
             .....:|::. ..:..|:  .||:|.|.|.....||..|:.:||.|:|:::.|.......|.|
  Rat   223 -TTGHHSPLFRGQQDTGPDRFSNVDYGVGYMLRLGAPTNKLVMGIPTFGKSFTLASSENQVGAP- 285

  Fly   318 VAEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDS 382
               ..|....|..|:..|.|::.|:|..|.......:.|...|....|:.
  Rat   286 ---ITGSGLPGRYTKEKGTLAYYEICDFLRGAEVHRILGQQVPFATKGNQ--------------- 332

  Fly   383 GENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHD-KFPILRQVKSKL 442
                 ||||:||::...|.:|:|.:.|.|..|..:..|||||...||: .||:...:|..|
  Rat   333 -----WVGYDDPESVKNKVKYLKNKQLAGAMVWAVDLDDFRGSFCGHNVHFPLTNAIKEAL 388

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	124/433 (29%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	114/409 (28%)
Chi3l1	NP_001296749.1	Glyco_18	31..365	CDD:214753	114/410 (28%)
Chi3l1	NP_001296749.1	GH18_chitolectin_chitotriosidase	32..388	CDD:119351	124/432 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166350380
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.940