DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and Cht5

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_650314.1	Gene:	Cht5 / 41687	FlyBaseID:	FBgn0038180	Length:	595	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	118/433 - (27%)
Similarity:	191/433 - (44%)	Gaps:	70/433 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLVGSLA---IGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSS 70
            ||:|.|.   ...:::..:..::||:...:..|.|:.:..|.|: || ..|||::|.:.|:|..|
  Fly     8 LLLGVLCSWPAATVASDQASRIVCYFSNWAVYRTGIGRYGLEDV-PA-DLCTHIIYSFIGVNDKS 70

  Fly    71 NKLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPF 135
            ..::..:.:||:|.|.  |.:.|.||:..|.:|:.::|||..:    ..:||..::...:.|..|
  Fly    71 WDVLVIDPELDVDQGG--FSKFTQLKKSNPNVKLEIAVGGWAE----GGSKYSQMVAVRDRRQSF 129

  Fly   136 INSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTAL 200
            |.|....:|.|.|||.||.|::|        |:..:          |.:..|      |:.|...
  Fly   130 IRSVVRFMKQYNFDGFDLDWEYP--------GATDR----------GGNYGD------KDKFLYF 170

  Fly   201 VRELKNAFRPDGYILGLSVLPNVNSSLF-----FDVPAIINNLDYVNLHTYDFQTPERNN--EVA 258
            |.||:.||..:|  .|..:...|..:.|     :.||.:...||.::..|||.    |.|  ..|
  Fly   171 VEELRRAFDREG--RGWEITMAVPVAKFRLNEGYHVPELCEALDAIHAMTYDL----RGNWAGFA 229

  Fly   259 DFPAPIYELNERN---PEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPV-- 318
            |..:|:|:.....   .:.|||..:..|.....||.|:.||:..|||.:.|:..:....:...
  Fly   230 DVHSPLYKRKHDQYAYEKLNVNDGLALWEEMGCPANKLVVGVPFYGRTFTLSNSNKNYNMGTYIN 294

  Fly   319 AEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSG 383
            .||.|.|| |..|...|.|::.|:|.::.:.:    ||........|     ...|.|:...
  Fly   295 KEAGGGAP-GPYTNASGFLAYYEICTEVMDKS----KGWTVEWDDAG-----MVPYTYKDTQ--- 346

  Fly   384 ENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGC 426
                |||||:..:..||.:::|:.|..|.....:..|||.|.|
  Fly   347 ----WVGYENEASIQIKMDFIKQRGYAGAMTWAIDMDDFHGMC 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	114/413 (28%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	109/404 (27%)
Cht5	NP_650314.1	Glyco_18	28..379	CDD:214753	109/405 (27%)
		GH18_chitolectin_chitotriosidase	29..397	CDD:119351	114/412 (28%)
		Trypan_PARP	367..469	CDD:114603	7/19 (37%)
		CBM_14	531..578	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	5	4.960