DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and chia.3

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_998378.1	Gene:	chia.3 / 406819	ZFINID:	ZDB-GENE-040426-2891	Length:	471	Species:	Danio rerio

Alignment Length:	449	Identity:	127/449 - (28%)
Similarity:	199/449 - (44%)	Gaps:	85/449 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLV 74
            |:..|::.....|.|..:.||:...|..|.|:.|....:::|.|  ||||:|.::.|| ..|:||
Zfish     6 LIAGLSLVLCHVAFSMEMACYFTNWSQYRPGIGKYTPANVDPYL--CTHLIYAFSIIN-QRNELV 67

  Fly    75 S---NNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNA-RIPF 135
            :   |:|        :|::....||.|.|.||.||:|||..     ..:...:::.|:.| |..|
Zfish    68 TYEWNDE--------TLYKAFNELKNKNPTLKTLLAVGGWN-----FGSAQFSIMVSNPANRKTF 119

  Fly   136 INSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTAL 200
            |.|....::|:|||||||.|::|        |:.|                  ...|.|:.||.|
Zfish   120 IQSTIKFLRTHGFDGLDLDWEYP--------GARG------------------SPPEDKQRFTLL 158

  Fly   201 VRELKNAFRPDGYILG-----LSVLPNVNSSLF---FDVPAIINNLDYVNLHTYDFQ-TPERNNE 256
            .:||..|:..:....|     |:...:......   :::..|...|:::|:.||||. |.||
Zfish   159 CKELVAAYEAESKATGNPQLMLTAAVSAGKGTIDDGYEIAEIAKYLNFINVMTYDFHGTWER--- 220

  Fly   257 VADFPAPIYELNERNPE---FNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPV 318
            .....:|:|:.::...:   ||.:|.::||..|..|..|:.:|.|.|||.::||......|.|
Zfish   221 FTGHNSPLYQGSKDEGDLIYFNTDYAMRYWRDNGTPVEKLRMGFAAYGRTFRLTSSDTSVGAP-- 283

  Fly   319 AEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSG 383
              |.|.|.|||.|:..|..|:.|:|..|.....|.:..     :||...||
Zfish   284 --ASGPASAGTYTREAGFWSYYEICGFLEGTTIQWIDD-----QKVPYATK-------------- 327

  Fly   384 ENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442
             |..|||::..::...|..|:|.:..||..|..|..|||.|........|::..:::.|
Zfish   328 -NSEWVGFDTKESYETKVRYLKDKNFGGAFVWALDLDDFAGQFCSQGNHPLMAHLRNLL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	122/431 (28%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	117/408 (29%)
chia.3	NP_998378.1	Glyco_18	24..363	CDD:214753	117/407 (29%)
		GH18_chitolectin_chitotriosidase	25..385	CDD:119351	122/428 (29%)
		ChtBD2	421..469	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592076
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840