DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and chia.2

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_998414.1	Gene:	chia.2 / 406338	ZFINID:	ZDB-GENE-040426-2014	Length:	470	Species:	Danio rerio

Alignment Length:	448	Identity:	131/448 - (29%)
Similarity:	202/448 - (45%)	Gaps:	83/448 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 LVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLV 74
            ||..|.:.....|.|..:.||:...|..|.|:.|....:::|.|  ||||.|.:|.|| .:|:|:
Zfish     6 LVAGLGLVLCHLAFSMEMGCYFTNWSQYRPGIGKYTPANVDPFL--CTHLFYAFAMIN-HANELI 67

  Fly    75 S---NNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPFI 136
            :   |:|        :|::....||...|.|:.||:|||    .:..:.::..::.|:..|..||
Zfish    68 TYEWNDE--------TLYKAFNELKNTNPHLRTLLAVGG----WNFGSTQFSIMVSSAANRQTFI 120

  Fly   137 NSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALV 201
            .|:...::||||||:||.|::|        ||.|                  ...|.|:.||.|.
Zfish   121 QSSIKFLRTYGFDGMDLDWEYP--------GSRG------------------SPPEDKQRFTLLC 159

  Fly   202 RELKNAFRPDGYILG-----LSVLPNVNSSLF---FDVPAIINNLDYVNLHTYDFQ-TPERNNEV 257
            :||..|:..:|...|     ||...:......   :::..|...||::|:.||||. |.||   .
Zfish   160 KELLEAYEAEGKATGRRRLMLSAAVSAGKGTIDDGYEIAEIAKYLDFINIMTYDFHGTWER---F 221

  Fly   258 ADFPAPIYELNERNPE---FNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVA 319
            ....:|:|:.::...:   ||.:|.::||..|..|..|:.:|.|||||.::||......|.|
Zfish   222 TGHNSPLYQGSKDEGDLVYFNTDYAMRYWRDNGTPVEKLRMGFATYGRTFRLTSSDTSVGAP--- 283

  Fly   320 EADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGE 384
             |.|.|.|||.|:..|..|:.|:|..|.....|.:..     :||...||
Zfish   284 -ASGPASAGTYTREAGFWSYYEICGFLEGTTVQWIDD-----QKVPYATK--------------- 327

  Fly   385 NGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442
            |..|||::..::...|..|:|.:..||..|..|..|||.|...|....|::..:::.|
Zfish   328 NSEWVGFDTKESYETKVRYLKDKKFGGAFVWALDLDDFAGQFCGQGNHPLMGHLRNLL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	125/430 (29%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	119/407 (29%)
chia.2	NP_998414.1	GH18_chitolectin_chitotriosidase	23..385	CDD:119351	125/429 (29%)
		Glyco_18	24..363	CDD:214753	119/406 (29%)
		CBM_14	423..468	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592070
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.940