DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and chia.1

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_998215.1	Gene:	chia.1 / 406323	ZFINID:	ZDB-GENE-040426-1994	Length:	455	Species:	Danio rerio

Alignment Length:	452	Identity:	111/452 - (24%)
Similarity:	206/452 - (45%)	Gaps:	87/452 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 SLLVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNK 72
            ::|.|...:..:....|..|:||....|..|.|..|.:..:::|.|  |||:||..|.|  |.:.
Zfish     5 TILAGLGILLSLQIVSSTKLVCYMTNWSQYRPGNGKFLPENIDPFL--CTHVVYALATI--SYDN 65

  Fly    73 LVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPFIN 137
            .::..|..|:|    |::.:..||:..||||..|||||..:.|.|    |:.::.:...|..||.
Zfish    66 QITTIEWNDVD----LYKSMNELKKVNPALKTQLSVGGLVNGVSP----YINMVATPENRKAFIR 122

  Fly   138 SAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVR 202
            :|...::.:.|||:|:.||:|.:     :||                     ..:.|:..|..::
Zfish   123 NALLFLRLHEFDGMDIDWQYPGH-----NGS---------------------PPQDKQRLTTFIK 161

  Fly   203 ELKNAFRPDG-------YILGLSV------LPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERN 254
            |:::|...:.       .:|.:.|      :.|.     ::...:.:.:|:|.:.:||:.  ...
Zfish   162 EMRDAIEQEAIDTKKTPLLLSIKVSAIKTTIENA-----YEAKEVASLVDFVTIMSYDYH--GHW 219

  Fly   255 NEVADFPAPIYELNERNPEF---NVNYQVKYWTGNRAPAAKINVGIATYGRAWKL-TKDSGLTGL 315
            :.:....:|::..:......   |:|..:::|.|:.|||.::.:|:.||||.:.| |..:|| |.
Zfish   220 DPITGHNSPLFRSSFDTGSIVHHNINSSLEFWLGSGAPADRLLLGLPTYGRTFMLSTSQTGL-GA 283

  Fly   316 PPVAEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSAD 380
            |    |:|.|.||..|:..|..|:.|:|   |..::..:...|          ::...||.
Zfish   284 P----ANGPADAGPYTREAGFWSYYEIC---PMESSVPIHWID----------EQMVPYAV---- 327

  Fly   381 DSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442
               :...|||:::.::...|.:::....|||.:|..|.||||.|....:..:|::..:::.|
Zfish   328 ---QGRAWVGFDNQESITAKVQWLNSLKLGGASVWTLDFDDFAGRFCYNGAYPLVNHLRNSL 386

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	107/432 (25%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	101/409 (25%)
chia.1	NP_998215.1	Glyco_18	23..364	CDD:214753	101/410 (25%)
		GH18_chitolectin_chitotriosidase	24..386	CDD:119351	107/431 (25%)
		ChtBD2	407..455	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592092
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	4	3.940