DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and Cht2

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001246550.1	Gene:	Cht2 / 38223	FlyBaseID:	FBgn0022702	Length:	484	Species:	Drosophila melanogaster

Alignment Length:	467	Identity:	120/467 - (25%)
Similarity:	192/467 - (41%)	Gaps:	88/467 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 LYALFSLLVGSLAIGQISAAGSHH---LLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYA 64
            |..|.:....||.....:..|..|   ::||....:..|.......:.:.:|.|  |||:||.:|
  Fly    16 LLLLLASTASSLWASVAARTGPLHDKVVVCYVSTWAVYRPEQGAYAIENFDPNL--CTHVVYAFA 78

  Fly    65 GINPSSNKLVSNNEKLDL--DLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLE 127
            |::.:...:.|.:...||  :.|...:.::|||||.:|.|||.|::||..:    .:..|.||:.
  Fly    79 GLDITQAAIKSLDPWQDLKEEYGKGGYEKMTGLKRSHPHLKVSLAIGGWNE----GSANYSTLVA 139

  Fly   128 SSNARIPFINSAHSLVKTYGFDGLDLGWQFP---KNKPKKVHGSIGKFWKGFKKIFSGDHVVDEK 189
            ::..|..|:....|.::.|.||||||.|::|   |.||
  Fly   140 NNLLRGRFVKQVSSFIRKYNFDGLDLDWEYPTQRKGKP--------------------------- 177

  Fly   190 AEEHKEAFTALVRELKNAFRPDGYILGLSVLPNVNSSLF---FDVPAIINNLDYVNLHTYDF--Q 249
              ..:|.|..|.:||:..|...|.:|..::  ..:..:.   :||..|...|||:::..||:  .
  Fly   178 --ADRENFVLLTKELREEFDEHGLLLTSAI--GASKKVIDEAYDVRQISRYLDYLHIMCYDYHGS 238

  Fly   250 TPERNNEVADFPAPIYELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTG 314
            ...|....|...||      .:...:|.:.:.|.....||..|:.:|:..|||.:| |..||.
  Fly   239 WDRRVGYNAPLTAP------ADDPLSVKFSIDYLLKLGAPPEKLVMGLPFYGRTFK-TLASGF-- 294

  Fly   315 LPPVAEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSA 379
            |..|:|  ||...|..|:..|.|.:.|:|..|.|..:       |..|:....|.:..:.:.|:.
  Fly   295 LNDVSE--GVGFKGPYTREDGFLGYNEICQTLSNQTS-------GWTREWDPQTSQVLAKSERNV 350

  Fly   380 DDSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGC-----TGHD--------- 430
            .....|  .|.|:...:.|.|..:...:.|.|:.|..:..|||.|.|     |..|
  Fly   351 FTQEIN--VVTYDSSRSIANKVLFAMSKRLAGVMVWSVDTDDFLGNCKLDEDTYEDFQKVTAAPK 413

  Fly   431 ----KFPILRQV 438
                .:|:||.:
  Fly   414 RSSQNYPLLRTI 425

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	115/444 (26%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	104/402 (26%)
Cht2	NP_001246550.1	Glyco_18	42..389	CDD:214753	104/403 (26%)
Cht2	NP_001246550.1	GH18_chitolectin_chitotriosidase	43..428	CDD:119351	114/440 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	5	4.960