DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and Cht8

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_611542.2	Gene:	Cht8 / 37390	FlyBaseID:	FBgn0034580	Length:	476	Species:	Drosophila melanogaster

Alignment Length:	458	Identity:	134/458 - (29%)
Similarity:	212/458 - (46%)	Gaps:	85/458 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     6 LFSLLVGSLAIGQISAA---GSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGIN 67
            |..||:|.:.:...|:|   .|.:::||....|..|.||.|..:.|::|.|  ||||:|.:.||.
  Fly     7 LVKLLLGVILMAASSSAQGNSSKNVVCYQGTWSVYRPGLGKFGMEDIDPFL--CTHLIYAFLGIE 69

  Fly    68 PSSN-KLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLL-ESSN 130
            .:.. :::.....|:.:.|....:....||.|.|.||.|::|||..     |.:|..:|: ...:
  Fly    70 ETGQLRVIDAYLDLEENSGRGNIKSFNALKLKNPVLKTLVAVGGWN-----EGSKRFSLVARDPS 129

  Fly   131 ARIPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKE 195
            .|..|::.....::.:|||||||.|::|..:                      |.:|   .|.:.
  Fly   130 KREKFVDDVVRFLQRHGFDGLDLDWEYPGQR----------------------HSLD---NEDRS 169

  Fly   196 AFTALVRELKNAFRPDGYILGLSV-LPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVAD 259
            .:...::|||....|.|:||..:| ....::.:.:|:||::..||.:|:..||...|.  ::|..
  Fly   170 NYITFLKELKEGLEPFGFILSAAVGSAQFSAEISYDIPAMVPYLDLINVMAYDLHGPW--DQVVG 232

  Fly   260 FPAPIY-------ELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKL-TKDSGLTGLP 316
            ..||:|       :.:.|..:.||:..||||....|||.|:.:|:..|||::.| |.:....|.|
  Fly   233 INAPLYAAEKDASDSSGRQQQLNVDAVVKYWLKAGAPAEKLILGVPFYGRSFTLATAEGNQPGAP 297

  Fly   317 PVAEADGVAPAGTQTQIPGLLSWPEVCAKLPN-------PANQHLKGADGPLRKVGDPTKRFGSY 374
            .:    |...||..::.||:|.:.|:|..:..       .|.|.:                  .|
  Fly   298 HI----GKGIAGNYSREPGVLGYNELCEMMEREEWTQKWEATQQV------------------PY 340

  Fly   375 AYRSADDSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVK 439
            |||...       |||||||.:.|:||:||....||||.:..|..|||||.| |...:|:|.::.
  Fly   341 AYRQRQ-------WVGYEDPRSLALKAQYVMDNHLGGIMIWSLESDDFRGTC-GQQPYPLLHEIN 397

  Fly   440 SKL 442
            ..|
  Fly   398 RVL 400

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	126/433 (29%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	117/410 (29%)
Cht8	NP_611542.2	GH18_chitolectin_chitotriosidase	31..400	CDD:119351	126/432 (29%)
		Glyco_18	31..379	CDD:214753	117/410 (29%)
		CBM_14	424..476	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463810
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	6	5.890