DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and Idgf1

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_477258.1	Gene:	Idgf1 / 34978	FlyBaseID:	FBgn0020416	Length:	439	Species:	Drosophila melanogaster

Alignment Length:	440	Identity:	235/440 - (53%)
Similarity:	316/440 - (71%)	Gaps:	11/440 - (2%)

- Green bases have known domain annotations that are detailed below.

  Fly     4 YALFSLLVGSLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINP 68
            :.||.:| |.|::..::.|.| :|:||||.||::|:||:|:...:|:.|||:||||||||||:..
  Fly     3 FQLFYIL-GLLSVTSLTHAAS-NLICYYDSNSYLRQGLAKMHTNELDLALQFCTHLVYGYAGLKS 65

  Fly    69 SSNKLVSNNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESS-NAR 132
            .:.:|.|    |::||....::.:|.|::|:|.||:|||||||:|..:...|||:.|||:: .|:
  Fly    66 GTLELFS----LNVDLDMFYYKDITALRQKFPQLKILLSVGGDRDVDEAHPNKYVELLEANRTAQ 126

  Fly   133 IPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAF 197
            ..||:|:..|:|..|||||||.:|.|:|||:|||||:|.:||.|||:|:||.|||.:|||||..|
  Fly   127 QNFIDSSMILLKRNGFDGLDLAFQLPRNKPRKVHGSLGSYWKSFKKLFTGDFVVDPQAEEHKSQF 191

  Fly   198 TALVRELKNAFRPDGYILGLSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVADFPA 262
            |.||..:|||||....:|.|:|||||||:.:||||.:....||:||..:||.||.||.|.|||.|
  Fly   192 TDLVGNIKNAFRSANLMLSLTVLPNVNSTWYFDVPKLHPQFDYINLAAFDFLTPLRNPEEADFTA 256

  Fly   263 PIYELNERN--PEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEADGVA 325
            ||:..:|:|  |..||.:|:.||..|..|..|:|:|||:|||||||:|.|||:|.|.|.|..|||
  Fly   257 PIFFQDEQNRLPHLNVEFQINYWLQNHCPGQKLNLGIASYGRAWKLSKGSGLSGAPIVHETCGVA 321

  Fly   326 PAGTQTQ-IPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWV 389
            |.|.|.| ..|||||||:|:||...|:...:|...|||||.|.|:::|:||.|.|||:|:.|||:
  Fly   322 PGGIQIQSAEGLLSWPEICSKLSQNASAQYRGELAPLRKVTDLTQKYGNYALRPADDNGDFGVWL 386

  Fly   390 GYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVK 439
            .::|||.|.|||.|.|.:||||||:.|||:|||||.||| .|:||||.:|
  Fly   387 SFDDPDFAGIKAVYAKGKGLGGIALFDLSYDDFRGLCTG-QKYPILRSIK 435

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	228/418 (55%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	214/396 (54%)
Idgf1	NP_477258.1	GH18_IDGF	23..438	CDD:119352	228/418 (55%)
Idgf1	NP_477258.1	Glyco_18	24..417	CDD:214753	214/396 (54%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45469722
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D227150at33208
OrthoFinder	1	1.000	-	-		FOG0008541
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	6	5.850