DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and Cht10

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001036422.1	Gene:	Cht10 / 3355116	FlyBaseID:	FBgn0250907	Length:	2286	Species:	Drosophila melanogaster

Alignment Length:	433	Identity:	133/433 - (30%)
Similarity:	211/433 - (48%)	Gaps:	78/433 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    24 SHH-LLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLVSNNEKLDLDLGSS 87
            ||: ::||:...::.|:|:.:....|:...|  |||::||:|.::.|  :||........|:.::
  Fly   963 SHYKVICYFTNWAWYRKGIGRFTPDDINTEL--CTHVIYGFAVLDYS--ELVLRTHDSWADVENN 1023

  Fly    88 LFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPFINSAHSLVKTYGFDGLD 152
            .:.:||.||.|  .:||.|::||..|:   :.:||..|:.|..||..|:..|...::.|||:|||
  Fly  1024 FYTRVTSLKSK--GIKVSLALGGWNDS---QGDKYSRLVRSPMARSRFVRHALEFIEKYGFEGLD 1083

  Fly   153 LGWQFPKNKPKKVHGSIGKFW-----KGFKKIFSGDHVVDEKAEEHKEAFTALVRELKNAFRPDG 212
            |.|::|            ..|     ||              :.|.|:.|||.|:||..||||.|
  Fly  1084 LDWEYP------------VCWQTECNKG--------------STEEKDGFTAWVQELSEAFRPRG 1122

  Fly   213 YILGLSVLPN---VNSSLFFDVPAIINNLDYVNLHTYDF--QTPERNNEVADFPAPIYELNERNP 272
            .:|..:|.|:   :::.  :|:|.:....|::.:.||||  ...::...|    ||:|...:.:.
  Fly  1123 LMLSTAVSPSRKIIDAG--YDIPQLSRYFDWIAVMTYDFHGHWDKKTGHV----APLYHHPDDDF 1181

  Fly   273 E-FNVNYQVKYWTGNRAPAAKINVGIATYGRAWKL--TKDSGLTGLPPVAEADGVAPAGTQTQIP 334
            | |||||.:.||....||:.|:.:||..||:::.|  |..|||.     |:|.....||..|:..
  Fly  1182 EYFNVNYSINYWMEKGAPSQKLVMGIPLYGQSFTLENTNSSGLN-----AKAPAPGEAGEFTRAA 1241

  Fly   335 GLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGYEDPDTAAI 399
            |.|::.|:|.::.....|          .|.|...|.|.|||:...       ||.|:.||....
  Fly  1242 GFLAYYEICERVNRQGWQ----------VVHDEFGRMGPYAYKGTQ-------WVSYDSPDMVRK 1289

  Fly   400 KAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442
            |:..|:...|||..|..|..|||:..| |:...|:|.::.:.|
  Fly  1290 KSLLVRSLKLGGGMVWALDLDDFKNRC-GNGVHPLLTEIHNVL 1331

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	130/429 (30%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	123/405 (30%)
Cht10	NP_001036422.1	Glyco_18	220..565	CDD:214753
		GH18_chitolectin_chitotriosidase	221..586	CDD:119351
		ChtBD2	697..737	CDD:214696
		CBM_14	801..848	CDD:279884
		CBM_14	875..918	CDD:279884
		Glyco_18	966..1310	CDD:214753	123/406 (30%)
		GH18_chitolectin_chitotriosidase	967..1331	CDD:119351	130/427 (30%)
		Glyco_18	1410..1753	CDD:214753
		GH18_chitolectin_chitotriosidase	1411..1774	CDD:119351
		ChtBD2	1834..1871	CDD:214696
		Glyco_18	1909..2253	CDD:214753
		GH18_chitolectin_chitotriosidase	1910..2274	CDD:119351
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463776
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	4	3.840