DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and chia.6

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_955897.2	Gene:	chia.6 / 322420	ZFINID:	ZDB-GENE-030131-1140	Length:	480	Species:	Danio rerio

Alignment Length:	454	Identity:	128/454 - (28%)
Similarity:	216/454 - (47%)	Gaps:	90/454 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 FSLLVG-SLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSS 70
            |..:.| |||:.....|.  .|:||:...|..|..:.|.:.::::|.|  ||||:|.::.|| :.
Zfish     4 FIFIAGFSLALCHFGLAS--QLVCYFTNWSQYRPDVGKYMPSNVDPHL--CTHLIYAFSIIN-NE 63

  Fly    71 NKLVS---NNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNAR 132
            |||.:   |:|        :|::...|||:..|.||.||:|||    .:....::.:::.:...|
Zfish    64 NKLTTYEWNDE--------TLYQSFNGLKQSNPNLKTLLAVGG----WNFGTTQFSSMVSTPQNR 116

  Fly   133 IPFINSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAF 197
            ..||.|:.:.::|:|||||||.|::|        ||.|                  ...|.|:.|
Zfish   117 QTFIQSSITFLRTHGFDGLDLDWEYP--------GSRG------------------SPPEDKQRF 155

  Fly   198 TALVRELKNAFRPDGYILGLSVL----------PNVNSSLFFDVPAIINNLDYVNLHTYDFQTPE 252
            |.|.:||..|::.:....|...|          .|:::.  :::..|...||::|:.||||....
Zfish   156 TLLCKELVEAYQAESAATGRPRLMLTAAVAAGKGNIDAG--YEIAEIAKYLDFINIMTYDFHGSW 218

  Fly   253 RNNEVADFPAPIY----ELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLT 313
            .:  |....:|:|    ::.:: ..:|.::.:.||....||..|:.:|.|.|||.::|:  |.::
Zfish   219 ES--VTGHNSPLYRGSGDIGDK-IYYNTDFAMTYWRDQGAPVEKLRMGFAAYGRTFRLS--SAVS 278

  Fly   314 GLPPVAEADGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRS 378
            |:.  |.|.|.|.|||.|:..|..|:.|:|..|.....|.:.....|             ||.:.
Zfish   279 GVG--APASGAASAGTYTREAGFWSYYEICTFLKQATVQQIVDQKVP-------------YATKG 328

  Fly   379 ADDSGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442
            .:       |||:::.::...|.:|:|.:|.||..|..|..|||.|...|..|:|::.|:::.|
Zfish   329 QE-------WVGFDNMESYKTKVDYLKEKGFGGAFVWALDLDDFSGQFCGQSKYPLIGQLRTLL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	121/432 (28%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	113/409 (28%)
chia.6	NP_955897.2	Glyco_18	22..363	CDD:214753	113/410 (28%)
		GH18_chitolectin_chitotriosidase	23..385	CDD:119351	121/431 (28%)
		CBM_14	433..479	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592058
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.840