DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and Cht12

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_726022.1	Gene:	Cht12 / 246535	FlyBaseID:	FBgn0050293	Length:	470	Species:	Drosophila melanogaster

Alignment Length:	426	Identity:	97/426 - (22%)
Similarity:	182/426 - (42%)	Gaps:	75/426 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    22 AGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYA-GINPSSNKLVSNNEKLDLDLG 85
            |..:::.|.||..|:..:|.|:.....|:..|  |||||.|.. |::..|.:|...::.|.|:..
  Fly    20 AKEYNVFCQYDLGSYYYKGRSQFFEWHLDSRL--CTHLVLGSGIGVDGDSGELRITDKILLLEKD 82

  Fly    86 SSLFRQVTGLK-RKYPAL-KVLLSVGGDKDTVDPENNKYLTLLESSNARIPFINSAHSLVKTYGF 148
                 :::.:| .|:.:: ||:.::||.::    :::.:..::.|...|..|.:|....:..:||
  Fly    83 -----KLSSVKTMKWDSIKKVMFTIGGWEE----DSSSFSRMVASPKKRDNFYSSMLEFMFRWGF 138

  Fly   149 DGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVRELKNAFRPDGY 213
            ||:.:.|::|                    ...|.|..|      ::.|..|:.||...||.:..
  Fly   139 DGVQIDWRYP--------------------TLLGGHPDD------RQNFVILLEELGLIFRKNQL 177

  Fly   214 ILGLSVLPNVNSSLF--FDVPAIINNLDYVNLHTYDFQTPERNNEVADFPAPIYELNERNPEFNV 276
            ||.::||...::.:.  :::|.|:|:.|:::|..:|.|.|.......:.|...|       |.:|
  Fly   178 ILMVAVLGRRDNRILESYNIPEIVNHSDFIHLMMHDEQDPYHLRLAYNAPLVGY-------EGSV 235

  Fly   277 NYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEADGVAPAGTQTQIPGLLSWPE 341
            ...:.:|..|.....|:.:||..:.|::.:.::....|    :...|......|:..||.:::.|
  Fly   236 TDSIMHWKRNGGAPEKLILGIPLFVRSFTMDRNQSTVG----SACKGPGRQTKQSHRPGFMTYNE 296

  Fly   342 VCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENGVWVGYEDPDTAAIKAEYVKR 406
            .|.:....:....:.|..|....||.                    ||.||:|.:...|...::.
  Fly   297 WCVQQSKWSRMFDQLAKVPYATRGDQ--------------------WVSYENPRSIWAKMHLLQE 341

  Fly   407 EGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442
            ..|||.....:..|||||.|  .::..:||.:.|.|
  Fly   342 HKLGGAMAWTIDVDDFRGRC--GEQHGLLRVIFSAL 375

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	95/420 (23%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	86/397 (22%)
Cht12	NP_726022.1	GH18_chitinase-like	25..375	CDD:299167	95/419 (23%)
		Glyco_hydro_18	47..355	CDD:279094	80/375 (21%)
		ChtBD2	394..438	CDD:214696
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45463816
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	115	1.000	Inparanoid score	I1336
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR11177
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X91
	6	5.890