DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Idgf4 and lmd-4

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_504862.2	Gene:	lmd-4 / 179121	WormBaseID:	WBGene00017233	Length:	2011	Species:	Caenorhabditis elegans

Alignment Length:	447	Identity:	98/447 - (21%)
Similarity:	178/447 - (39%)	Gaps:	111/447 - (24%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 SAAGSHHLLCYYDG---NSFVREGLSKLILTDLEPALQYCTHLVYGYAGI-NPSSNKLVSNNEKL 80
            :|:....::.||.|   .......|.||            ||:::.:..: ...|.|..:.:|.
Worm  1474 AASCGKRIVGYYTGWGDREITENQLKKL------------THVIFAFVAMYEDGSVKFGAVSED- 1525

  Fly    81 DLDLG----SSLFRQVTGLKRKYPA----LKVLLSVGGDKDTVDPENNKYL-TLLESSNARIPFI 136
              |.|    ....|:...:|:|..|    ::||.:|||      .:|::|. ::...|..|..|:
Worm  1526 --DSGPQAAKKAERRFLNMKKKARAANSGVRVLFAVGG------WDNSQYFSSVAADSGKRKKFV 1582

  Fly   137 NSAHSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALV 201
            :|..|.|:....||:||.|::|.:..|.                :.:||  :..:|.:|.|:.:.
Worm  1583 DSIASFVEDQKIDGVDLDWEYPDSNGKD----------------AKNHV--QLIKEIREKFSEMA 1629

  Fly   202 RELKNAFRPDGYILGL-SVLPNVNSSLFFDVPAIINNLDYVNLHTYDF--QTPERNNEVADFPAP 263
            ::.|   |.|.|::.| |.....|....:|:..|:...|::|:.|||:  ....:.......|||
Worm  1630 KKKK---RKDPYVITLASAAGEWNLRKGYDLKGILKYADFINVMTYDYYGAWESKWGAYTGTPAP 1691

  Fly   264 IY--ELNERNPEFNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEADGV-- 324
            :|  .|...:.:.|.::.:|::.......:::|:|:..|||.||       ..|.|:.::|.:
Worm  1692 LYFGSLKGFSGKLNADFSMKFYACKTEKPSQLNMGVPFYGRYWK-------NVLGPIDKSDNMWR 1749

  Fly   325 --APAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDP------TKRFGSYAYRSADD 381
              ||...:.: .|.:.|..:..:..|      ||:.....|...|      .|:|
Worm  1750 TAAPQNGKYE-GGYVGWRNLAKEGWN------KGSASWHEKTKTPYIMNNGAKKF---------- 1797

  Fly   382 SGENGVWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDD----------FRGGCTG 428
                   :|:|:..:...|.:|.....|||:.:..|..||          ..|.|:|
Worm  1798 -------LGFENERSLKEKMKYATDRNLGGLMIWALDLDDDADTLLNLVSSAGLCSG 1847

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	97/441 (22%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	92/420 (22%)
lmd-4	NP_504862.2	LysM	25..65	CDD:197609
		LysM	79..120	CDD:197609
		LysM	142..185	CDD:197609
		LysM	209..250	CDD:197609
		LysM	270..313	CDD:197609
		LysM	334..377	CDD:197609
		LysM	401..444	CDD:197609
		LysM	469..509	CDD:197609
		LysM	550..590	CDD:197609
		LysM	635..678	CDD:197609
		LysM	710..750	CDD:197609
		LysM	760..802	CDD:197609
		LysM	876..919	CDD:197609
		Self-incomp_S1	1359..1433	CDD:283566
		Glyco_18	1480..1825	CDD:214753	91/417 (22%)
		GH18_chitinase-like	1481..1824	CDD:299167	91/415 (22%)
		ChtBD1_GH18_2	1873..1924	CDD:211315
		ChtBD1_GH18_2	1951..2002	CDD:211315
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160164378
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.700