DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Idgf4 and chia.5

DIOPT Version :9

Sequence 1:	NP_001285068.1	Gene:	Idgf4 / 31926	FlyBaseID:	FBgn0026415	Length:	442	Species:	Drosophila melanogaster
Sequence 2:	NP_001103511.2	Gene:	chia.5 / 100003900	ZFINID:	ZDB-GENE-071004-113	Length:	481	Species:	Danio rerio

Alignment Length:	446	Identity:	123/446 - (27%)
Similarity:	205/446 - (45%)	Gaps:	87/446 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 SLAIGQISAAGSHHLLCYYDGNSFVREGLSKLILTDLEPALQYCTHLVYGYAGINPSSNKLVS-- 75
            |||:.....|.  .|:||:...|..|..:.|.:.::::|.|  ||||:|.::.|| :.|||.:
Zfish    11 SLALCHFGLAS--QLICYFTNWSQYRPDVGKYMPSNVDPHL--CTHLIYAFSIIN-NENKLTTYE 70

  Fly    76 -NNEKLDLDLGSSLFRQVTGLKRKYPALKVLLSVGGDKDTVDPENNKYLTLLESSNARIPFINSA 139
             |:|        :|::...|||:....||.||:|||    .:..:.::.:::.....|..||.|:
Zfish    71 WNDE--------TLYQSFNGLKQSNSNLKTLLAVGG----WEFGSAQFSSMVSMPQNRQTFIQSS 123

  Fly   140 HSLVKTYGFDGLDLGWQFPKNKPKKVHGSIGKFWKGFKKIFSGDHVVDEKAEEHKEAFTALVREL 204
            .:.::|:|||||||.|::|        ||.|                  ...|.|:.||.|.:||
Zfish   124 ITFLRTHGFDGLDLDWEYP--------GSRG------------------SPPEDKQRFTLLCKEL 162

  Fly   205 KNAFRPDGYILG----------LSVLPNVNSSLFFDVPAIINNLDYVNLHTYDFQTPERNNEVAD 259
            ..|::.:....|          .:|...:::.  :::..|...||::|:.||||...:.|  :..
Zfish   163 VEAYQAESAATGRPRLMLTAAVAAVKGIIDAG--YEIAEIAKYLDFINIMTYDFHGSQDN--ITG 223

  Fly   260 FPAPIYELNERNPE---FNVNYQVKYWTGNRAPAAKINVGIATYGRAWKLTKDSGLTGLPPVAEA 321
            ..:|:|..:....:   :|.::.:.||....||..|:.:|.|.|||.::|:......|.|    |
Zfish   224 HNSPLYRDSGDTGDQIYYNTDFAMNYWRDQGAPVEKLRMGFAAYGRTFRLSSADNGVGAP----A 284

  Fly   322 DGVAPAGTQTQIPGLLSWPEVCAKLPNPANQHLKGADGPLRKVGDPTKRFGSYAYRSADDSGENG 386
            .|.|.|||.|:..|..|:.|:|..|.....|.:.....|             ||.:..:
Zfish   285 SGAALAGTYTREAGFWSYYEICTFLQGAIVQQIVDQKVP-------------YATKGQE------ 330

  Fly   387 VWVGYEDPDTAAIKAEYVKREGLGGIAVVDLSFDDFRGGCTGHDKFPILRQVKSKL 442
             |||::|.::...|.:|:|.:|.||..|..|..|||.|...|..|:|::..:.:.|
Zfish   331 -WVGFDDQESYETKVDYLKEKGFGGAFVWSLDLDDFSGQFCGQGKYPLIGHLHTLL 385

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Idgf4	NP_001285068.1	GH18_IDGF	26..442	CDD:119352	118/431 (27%)
Idgf4	NP_001285068.1	Glyco_18	27..420	CDD:214753	111/408 (27%)
chia.5	NP_001103511.2	Glyco_18	22..363	CDD:214753	111/409 (27%)
		GH18_chitolectin_chitotriosidase	23..381	CDD:119351	118/426 (28%)
		CBM_14	433..479	CDD:279884
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170592052
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG3325
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830