DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1986 and LIPG

DIOPT Version :9

Sequence 1:	NP_001285067.1	Gene:	CG1986 / 31925	FlyBaseID:	FBgn0030162	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	XP_005258447.1	Gene:	LIPG / 9388	HGNCID:	6623	Length:	536	Species:	Homo sapiens

Alignment Length:	271	Identity:	94/271 - (34%)
Similarity:	131/271 - (48%)	Gaps:	29/271 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    94 KLALFLHGWNDQG-SKDWVQELLLTWTLFDSNYNVCVVDWGNLSQNDYKSASMSIFDVGLTVAGI 157
            |....:|||...| .::|:.:|:......:.:.||.||||..|:...|..|..:...||.::|.:
Human   120 KTFFIIHGWTMSGIFENWLHKLVSALHTREKDANVVVVDWLPLAHQLYTDAVNNTRVVGHSIARM 184

  Fly   158 IMALEELRPNHFHRSNVTLAGYSLGAHAAGYAGAVLEGQVEQIIGLDPAGPLFSLPAEVAPKYRL 222
            :..|:|  .:.|...||.|.|||||||.|||||..::|.|.:|.|||||||:|. .|::  ..||
Human   185 LDWLQE--KDDFSLGNVHLIGYSLGAHVAGYAGNFVKGTVGRITGLDPAGPMFE-GADI--HKRL 244

  Fly   223 DPGDAQFVQVLHT----SGGSLGTSLKCGHADFYPNGGRAPQTNCKMFANLRDMQN-------TN 276
            .|.||.||.||||    .|.|:|..:..||.|.|||||.. |..|    .|.|:..       |.
Human   245 SPDDADFVDVLHTYTRSFGLSIGIQMPVGHIDIYPNGGDF-QPGC----GLNDVLGSIAYGTITE 304

  Fly   277 PVSCSHSAAAIFFRQSM-DPEYPFVGYECGSYREFAAGYCDGNRKAR---FGIHSQR---RAQGS 334
            .|.|.|..|...|..|: :.:.|...::|.....|..|.|...||.|   .|.::::   :....
Human   305 VVKCEHERAVHLFVDSLVNQDKPSFAFQCTDSNRFKKGICLSCRKNRCNSIGYNAKKMRNKRNSK 369

  Fly   335 FYFRTAPQQPY 345
            .|.:|....|:
Human   370 MYLKTRAGMPF 380

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1986	NP_001285067.1	Pancreat_lipase_like	67..341	CDD:238363	93/265 (35%)
LIPG	XP_005258447.1	Pancreat_lipase_like	85..376	CDD:238363	93/265 (35%)
		lipo_lipase	86..521	CDD:132274	94/271 (35%)
		PLAT_LPL	383..519	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	2.010