Protein Alignment CG1986 and PNLIP

DIOPT Version :10

• Sequence 1: NP_572590.1
• Gene: CG1986 / 31925
• FlyBaseID: FBgn0030162
• Length: 404
• Species: Drosophila melanogaster
• Sequence 2: NP_000927.1
• Gene: PNLIP / 5406
• HGNCID: 9155
• Length: 465
• Species: Homo sapiens
• Alignment Length: 341
• Identity: 102/341 - (29%)
• Similarity: 141/341 - (41%)
• Gaps: 70/341 - (20%)

  Fly     9 LLLGC----------LLCLLGDVPRIEAFHR------WSPMMKAFRYLQETMLRNSLERAHLNHG 57
            ||||.          |.|...|.|......|      |||.....|:|..|.     |..:....
Human     9 LLLGAVAGKEVCYERLGCFSDDSPWSGITERPLHILPWSPKDVNTRFLLYTN-----ENPNNFQE 68

  Fly    58 IVFECRTISAKDFGNEVHFNLQLGDLRGFRRLDPNKKLALFLHGWNDQGSKDWVQELLLTWTLFD 122
            :..:..:||..:|                   ..|:|....:||:.|:|.::|:..:.......:
Human    69 VAADSSSISGSNF-------------------KTNRKTRFIIHGFIDKGEENWLANVCKNLFKVE 114

  Fly   123 SNYNVCVVDWGNLSQNDYKSASMSIFDVGLTVAGIIMALEELRPNHFHRSNVTLAGYSLGAHAAG 187
            |...:| |||...|:..|..||.:|..||..||..:..|:.  ...:..|||.:.|:||||||||
Human   115 SVNCIC-VDWKGGSRTGYTQASQNIRIVGAEVAYFVEFLQS--AFGYSPSNVHVIGHSLGAHAAG 176

  Fly   188 YAGAVLEGQVEQIIGLDPAGPLFSLPAEVAPKYRLDPGDAQFVQVLHTSGGSL------GTSLKC 246
            .||....|.:.:|.|||||.|.|....|:.   ||||.||:||.|:||.|..:      |.|...
Human   177 EAGRRTNGTIGRITGLDPAEPCFQGTPELV---RLDPSDAKFVDVIHTDGAPIVPNLGFGMSQVV 238

  Fly   247 GHADFYPNGGRAPQTNCK------------MFANLRDMQNTNPVSCSHSAAAIFFRQSMDPEYPF 299
            ||.||:|||| .....||            ::...||.     .:|:|..:..::..|:.....|
Human   239 GHLDFFPNGG-VEMPGCKKNILSQIVDIDGIWEGTRDF-----AACNHLRSYKYYTDSIVNPDGF 297

  Fly   300 VGYECGSYREFAAGYC 315
            .|:.|.||..|.|..|
Human   298 AGFPCASYNVFTANKC 313

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG1986	NP_572590.1	Pancreat_lipase_like	67..341	CDD:238363	84/267 (31%)
PNLIP	NP_000927.1	Lipase	17..352	CDD:395099	98/333 (29%)
		PLAT_PL	355..465	CDD:238857