DRSC/TRiP Functional Genomics Resources

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Protein Alignment CG1986 and LPL

DIOPT Version :10

Sequence 1:NP_572590.1 Gene:CG1986 / 31925 FlyBaseID:FBgn0030162 Length:404 Species:Drosophila melanogaster
Sequence 2:NP_000228.1 Gene:LPL / 4023 HGNCID:6677 Length:475 Species:Homo sapiens


Alignment Length:317 Identity:109/317 - (34%)
Similarity:142/317 - (44%) Gaps:51/317 - (16%)


- Green bases have known domain annotations that are detailed below.


  Fly    50 ERAHLNHGIVFECRTISAKDFGNEVHFNLQLGDLRGFRRLDPNKKLALFLHGWNDQGS-KDWVQE 113
            :..||..|:.....|         .|||             .:.|..:.:|||...|. :.||.:
Human    52 DTCHLIPGVAESVAT---------CHFN-------------HSSKTFMVIHGWTVTGMYESWVPK 94

  Fly   114 LLLTWTLFDSNYNVCVVDWGNLSQNDYKSASMSIFDVGLTVAGIIMALEELRPNHFHRSNVTLAG 178
            |:......:.:.||.||||.:.:|..|..::.....||..||..|..:||  ..::...||.|.|
Human    95 LVAALYKREPDSNVIVVDWLSRAQEHYPVSAGYTKLVGQDVARFINWMEE--EFNYPLDNVHLLG 157

  Fly   179 YSLGAHAAGYAGAVLEGQVEQIIGLDPAGPLFSLPAEVAPKYRLDPGDAQFVQVLHT-----SGG 238
            |||||||||.||::...:|.:|.|||||||.|.. || ||. ||.|.||.||.||||     .|.
Human   158 YSLGAHAAGIAGSLTNKKVNRITGLDPAGPNFEY-AE-APS-RLSPDDADFVDVLHTFTRGSPGR 219

  Fly   239 SLGTSLKCGHADFYPNGGRAPQTNCKMFANLR--------DMQNTNPVSCSHSAAA-IFFRQSMD 294
            |:|.....||.|.|||||.. |..|.:...:|        |:...  |.|||..:. :|....::
Human   220 SIGIQKPVGHVDIYPNGGTF-QPGCNIGEAIRVIAERGLGDVDQL--VKCSHERSIHLFIDSLLN 281

  Fly   295 PEYPFVGYECGSYREFAAGYCDGNRKAR-----FGIHSQRRAQGS-FYFRTAPQQPY 345
            .|.|...|.|.|...|..|.|...||.|     :.|:..|..:.| .|.:|..|.||
Human   282 EENPSKAYRCSSKEAFEKGLCLSCRKNRCNNLGYEINKVRAKRSSKMYLKTRSQMPY 338

Known Domains:


Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 592.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.

GeneSequenceDomainRegion External IDIdentity
CG1986NP_572590.1 Pancreat_lipase_like 67..341 CDD:238363 102/294 (35%)