DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1986 and lipca

DIOPT Version :9

Sequence 1:	NP_001285067.1	Gene:	CG1986 / 31925	FlyBaseID:	FBgn0030162	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_957316.1	Gene:	lipca / 393997	ZFINID:	ZDB-GENE-040426-1361	Length:	514	Species:	Danio rerio

Alignment Length:	288	Identity:	91/288 - (31%)
Similarity:	135/288 - (46%)	Gaps:	33/288 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    82 DLRGFRRLDPNKKLALFLHGWNDQGSKD-WVQELLLTWTLFDSNYNVCVVDWGNLSQNDYKSASM 145
            |..||....|   ||:.:|||:..|..: |:..|.......:.|.||.:.||..|:...|..|:.
Zfish    70 DACGFNSSLP---LAIIIHGWSVDGMMEKWISRLASALKSSEGNINVLIADWLTLAHQHYPIAAQ 131

  Fly   146 SIFDVGLTVAGIIMALEELRPNHFHRSNVTLAGYSLGAHAAGYAGA--VLEGQ-VEQIIGLDPAG 207
            :...||..:|.::..||:.:  .|....|.|.|||||||.:|:||:  .:.|: :.:|.||||||
Zfish   132 NTRIVGQDIAHLLSWLEDFK--QFPLGKVHLIGYSLGAHISGFAGSNLAMSGRTLGRITGLDPAG 194

  Fly   208 PLFSLPAEVAPKYRLDPGDAQFVQVLHT-----SGGSLGTSLKCGHADFYPNGGRAPQTNCKM-- 265
            |:|.   .::...||.|.||:||..:||     .|.|:|......|.||||||| :.|..|::
Zfish   195 PMFE---GMSHTDRLSPEDAKFVDAIHTFTLQRMGLSVGIKQPVAHFDFYPNGG-SFQPGCQLHM 255

  Fly   266 ---FANLRD---MQNTNPVSCSHSAAA-IFFRQSMDPEYPFVGYECGSYREFAAGYCDGNRKAR- 322
               :|:|..   |.....|.|:|..|. :|....::.:...:.|:|.....|..|.|...||.|
Zfish   256 QNIYAHLAQHGIMGFEQTVKCAHERAVHLFIDSLLNKDKQIMAYKCSDNTAFDKGNCLDCRKNRC 320

  Fly   323 ----FGIHSQRRAQGS-FYFRTAPQQPY 345
                :.|...|..:.. .:.:|....||
Zfish   321 NTLGYDIKKVRTGKSKRLFLKTRSHMPY 348

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1986	NP_001285067.1	Pancreat_lipase_like	67..341	CDD:238363	89/282 (32%)
lipca	NP_957316.1	lipo_lipase	44..488	CDD:132274	91/288 (32%)
		Pancreat_lipase_like	54..344	CDD:238363	89/282 (32%)
		PLAT_LPL	351..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	3	2.910