DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1986 and Lipg

DIOPT Version :9

Sequence 1:	NP_001285067.1	Gene:	CG1986 / 31925	FlyBaseID:	FBgn0030162	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_001012759.1	Gene:	Lipg / 291437	RGDID:	1310740	Length:	493	Species:	Rattus norvegicus

Alignment Length:	313	Identity:	107/313 - (34%)
Similarity:	143/313 - (45%)	Gaps:	42/313 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    58 IVFECRTISAKDFGNEVHFNLQLGDLR-----GFRRLDPNKKLALFLHGWNDQGS-KDWVQELLL 116
            :.|..||  :||..:| ..||.|||.:     ||   :...|....:|||...|. :.|:.:|:.
  Rat    51 VTFNIRT--SKDPEHE-GCNLSLGDSKLLENCGF---NMTAKTFFIIHGWTMSGMFESWLHKLVS 109

  Fly   117 TWTLFDSNYNVCVVDWGNLSQNDYKSASMSIFDVGLTVAGIIMALEELRPNHFHRSNVTLAGYSL 181
            .....:...||.||||..|:...|..|..:...||..|||::..|:|  ...|...:|.|.||||
  Rat   110 ALQTREKEANVVVVDWLPLAHQLYIDAVSNTRVVGRRVAGMLNWLQE--KGEFSLGDVHLIGYSL 172

  Fly   182 GAHAAGYAGAVLEGQVEQIIGLDPAGPLFSLPAEVAPKYRLDPGDAQFVQVLHT----SGGSLGT 242
            |||.|||||..::|.|.:|.|||||||:|.   .|....||.|.||.||.||||    .|.|:|.
  Rat   173 GAHVAGYAGNFVKGTVGRITGLDPAGPMFE---GVDINRRLSPDDADFVDVLHTYTLSFGLSIGI 234

  Fly   243 SLKCGHADFYPNGGRAPQTNCKM--------FANLRDMQNTNPVSCSHSAAAIFFRQSM-DPEYP 298
            .:..||.|.|||||.. |..|..        :..:.:|     |.|.|..|...|..|: :.:.|
  Rat   235 RMPVGHIDIYPNGGDF-QPGCGFNDVMGSFAYGTISEM-----VKCEHERAVHLFVDSLVNQDKP 293

  Fly   299 FVGYECGSYREFAAGYCDGNRKAR-----FGIHSQRRAQGS-FYFRTAPQQPY 345
            ...::|.....|..|.|...||.|     :.....|:.:.| .|.:|....|:
  Rat   294 SFAFQCTDPNRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKMYLKTRAGMPF 346

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1986	NP_001285067.1	Pancreat_lipase_like	67..341	CDD:238363	103/298 (35%)
Lipg	NP_001012759.1	Pancreat_lipase_like	51..342	CDD:238363	106/307 (35%)
		lipo_lipase	53..488	CDD:132274	107/311 (34%)
		Heparin-binding. /evidence=ECO:0000250	327..339		3/11 (27%)
		PLAT_LPL	349..485	CDD:238856
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	3	3.010