DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG1986 and Pnlip

DIOPT Version :9

Sequence 1:	NP_001285067.1	Gene:	CG1986 / 31925	FlyBaseID:	FBgn0030162	Length:	404	Species:	Drosophila melanogaster
Sequence 2:	NP_037293.2	Gene:	Pnlip / 25702	RGDID:	3360	Length:	465	Species:	Rattus norvegicus

Alignment Length:	340	Identity:	98/340 - (28%)
Similarity:	140/340 - (41%)	Gaps:	68/340 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 LLLGC----------LLCLLGDVPRIEAFHR------WSPMMKAFRYLQETMLRNSLERAHLNHG 57
            :|||.          |.|...|.|......|      |||.....|:|..|
  Rat     9 VLLGAVAGKEVCFDKLGCFSDDAPWSGTIDRPLKALPWSPAQINTRFLLYT-------------- 59

  Fly    58 IVFECRTISAKDFGNEVHFNLQ--LGDLRGFR--RLDPNKKLALFLHGWNDQGSKDWVQELLLTW 118
                          ||...|.|  ..|....|  ....|:|..:.:||:.|:|.::|:.::....
  Rat    60 --------------NENQDNYQKITSDASSIRNSNFKTNRKTRIIIHGFIDKGEENWLSDMCKNM 110

  Fly   119 TLFDSNYNVCVVDWGNLSQNDYKSASMSIFDVGLTVAGIIMALEELRPNHFHRSNVTLAGYSLGA 183
            ...:|...:| |||...|:..|..|:.::..||..||.::..|:.  ...:...||.|.|:|||:
  Rat   111 FKVESVNCIC-VDWKGGSRATYTQATQNVRVVGAEVALLVNVLKS--DLGYSPDNVHLIGHSLGS 172

  Fly   184 HAAGYAGAVLEGQVEQIIGLDPAGPLF-SLPAEVAPKYRLDPGDAQFVQVLHTSGGSL------G 241
            |.||.||....|.:.:|.|||.|.|.| ..|.||    ||||.|||||..:||....:      |
  Rat   173 HVAGEAGKRTFGAIGRITGLDAAEPYFQGTPEEV----RLDPTDAQFVDAIHTDAAPIIPNLGFG 233

  Fly   242 TSLKCGHADFYPNGG-RAPQTNCKMFANLRDM----QNTNP-VSCSHSAAAIFFRQSMDPEYPFV 300
            .|...||.||:|||| ..|.....:.:.:.|:    :.|.. .:|:|..:..::..|:.....|.
  Rat   234 MSQTVGHLDFFPNGGMEMPGCQKNILSQIVDIDGIWEGTRDFAACNHLRSYKYYTDSIVNPTGFS 298

  Fly   301 GYECGSYREFAAGYC 315
            |:.|.||..|:|..|
  Rat   299 GFSCSSYNVFSANKC 313

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG1986	NP_001285067.1	Pancreat_lipase_like	67..341	CDD:238363	84/266 (32%)
Pnlip	NP_037293.2	Lipase	17..352	CDD:395099	95/332 (29%)
Pnlip	NP_037293.2	PLAT_PL	355..465	CDD:238857
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_28N19
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910